Atomic layer deposition of nanoporous biomaterials

Due to its chemical stability, uniform pore size, and high pore density, nanoporous alumina is being investigated for use in biosensing, drug delivery, hemodialysis, and other medical applications. In recent work, we have examined the use of atomic layer deposition for coating the surfaces of nanopo...

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Bibliographic Details
Published in:Materials today (Kidlington, England) England), 2010-03, Vol.13 (3), p.60-64
Main Authors: Narayan, Roger J, Adiga, Shashishekar P, Pellin, Michael J, Curtiss, Larry A, Stafslien, Shane, Chisholm, Bret, Monteiro-Riviere, Nancy A, Brigmon, Robin L, Elam, Jeffrey W
Format: Article
Language:English
Subjects:
Escherichia coli
Staphylococcus aureus
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Summary:Due to its chemical stability, uniform pore size, and high pore density, nanoporous alumina is being investigated for use in biosensing, drug delivery, hemodialysis, and other medical applications. In recent work, we have examined the use of atomic layer deposition for coating the surfaces of nanoporous alumina membranes. Zinc oxide coatings were deposited on nanoporous alumina membranes using atomic layer deposition. The zinc oxide-coated nanoporous alumina membranes demonstrated antimicrobial activity against Escherichia coli and Staphylococcus aureus bacteria. These results suggest that atomic layer deposition is an attractive technique for modifying the surfaces of nanoporous alumina membranes and other nanostructured biomaterials.
ISSN:1369-7021
1873-4103
DOI:10.1016/S1369-7021(10)70035-3