CTX-M and ampC b-lactamases contributing to increased prevalence of ceftriaxone-resistant Escherichia coli in Changi General Hospital, Singapore

Data from an 800-bed hospital showed an increase in the incidence density of ceftriaxone-resistant Escherichia coli, from 13.1 to 21.7 per 100a?000 inpatient days over a 4-year period. Detailed testing performed on 54 E. coli isolates showed bla CTX-M extended-spectrum b-lactamase (ESBL) genes (n =...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2010-02, Vol.66 (2), p.210-213
Main Authors: Tan, Thean Yen, Ng, Lily Siew Yong, He, Jie, Hsu, Li Yang
Format: Article
Language:English
Subjects:
Escherichia coli
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Summary:Data from an 800-bed hospital showed an increase in the incidence density of ceftriaxone-resistant Escherichia coli, from 13.1 to 21.7 per 100a?000 inpatient days over a 4-year period. Detailed testing performed on 54 E. coli isolates showed bla CTX-M extended-spectrum b-lactamase (ESBL) genes (n = 37) and bla CMY-like ampC genes (n = 15). Typing data showed only limited clonal transmission in isolates with ESBL.
ISSN:0732-8893
DOI:10.1016/j.diagmicrobio.2009.08.019