Using clinical cardiovascular risk scores to predict coronary artery plaque severity and stenosis detected by CT coronary angiography in asymptomatic Chinese subjects

• Published in: The International Journal of Cardiovascular Imaging 2011-06, Vol.27 (5), p.669-678
• Main Authors: Lee, Bai-Chin, Lee, Wen-Jeng, Hsu, Hsiu-Ching, Chien, Kuo-Liong, Shih, Tiffany Ting-Fang, Chen, Ming-Fong
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Asian Continental Ancestry Group; Asymptomatic Diseases; Cardiac Imaging; Cardiology; Chi-Square Distribution; China - epidemiology; Coronary Angiography - methods; Coronary Stenosis - diagnostic imaging; Coronary Stenosis - ethnology; Coronary Stenosis - etiology; Female; Humans; Imaging; Male; Medicine; Medicine & Public Health; Middle Aged; Original Paper; Plaque, Atherosclerotic - diagnostic imaging; Plaque, Atherosclerotic - ethnology; Plaque, Atherosclerotic - etiology; Predictive Value of Tests; Radiology; Risk Assessment; Risk Factors; Severity of Illness Index; Taiwan; Tomography, X-Ray Computed; Young Adult
• ISSN: 1569-5794; 1573-0743; 1875-8312
• DOI: 10.1007/s10554-011-9874-6

We aimed to determine whether the Framingham risk score (FRS), systematic coronary risk evaluation (SCORE), and Chinese multi-provincial cohort study (CMCS) could predict anatomic severity of coronary plaques. From January 2007 to October 2010, we performed a contrast-enhanced 64-slice or 256-slice multidetector computed tomography coronary angiography as part of a health check-up protocol in 806 asymptomatic subjects (70.5% male, 56 ± 9 year-old). Risk scores significantly correlated with calcium volume score, plaque stenosis score and plaque distribution score ( P