Myocardial Perfusion and Exercise Capacity 12 Years After Arterial Switch Surgery for D-Transposition of the Great Arteries

Peak exercise myocardial perfusion was evaluated in patients with D-transposition of the great arteries 12 years after the arterial switch operation (SWITCH) to evaluate coronary perfusion. Gas-exchange measurements were used to assess cardiac limiting factors to exercise capacity in SWITCH patients...

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Bibliographic Details
Published in:Pediatric cardiology 2011-08, Vol.32 (6), p.785-791
Main Authors: Sterrett, Lauren E., Schamberger, Marcus S., Ebenroth, Eric S., Siddiqui, Aslam R., Hurwitz, Roger A.
Format: Article
Language:English
Subjects:
Adolescent
Arteries
Cardiac patients
Cardiac Surgery
Cardiology
Child
Comparative analysis
Coronary Circulation
Exercise Tolerance - physiology
Female
Follow-Up Studies
Heart beat
Heart Rate
Humans
Male
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Myocardial Perfusion Imaging - methods
Myocardium - metabolism
Original Article
Oxygen Consumption - physiology
Postoperative Period
Time Factors
Transposition of great arteries
Transposition of Great Vessels - metabolism
Transposition of Great Vessels - physiopathology
Transposition of Great Vessels - surgery
Treatment Outcome
Vascular Surgery
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Summary:Peak exercise myocardial perfusion was evaluated in patients with D-transposition of the great arteries 12 years after the arterial switch operation (SWITCH) to evaluate coronary perfusion. Gas-exchange measurements were used to assess cardiac limiting factors to exercise capacity in SWITCH patients when compared to healthy gender-matched controls (CON). Peak myocardial perfusion was evaluated in 42 patients 12 years post-SWITCH, using technetium-99 m (Tetrofosmin). SWITCH exercise data was compared to 42 gender-matched controls (CON). One symptomatic and one asymptomatic SWITCH patient had abnormal exercise myocardial perfusion; both patients had variant coronary anatomy preoperatively. SWITCH patients had lower VO 2peak ( p  
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-011-9975-y