A fatal case of mesenchymal chondrosarcoma of the mandible

A 34-year-old man presented with an expansile, erosive tumor involving the left side of the mandible, with secondary invasion into the maxilla, measuring 13 Χ 7 cm. Microscopic analysis revealed a malignant small round cell neoplasm with focal cartilaginous differentiation. Immunohistochemical analy...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2011-04, Vol.7 (2), p.192-194
Main Authors: Krishnamurthy, Arvind, Vaidhyanathan, Anitha, Srinivas, Satish, Majhi, Urmila
Format: Article
Language:English
Subjects:
Adult
Cancer
Care and treatment
Case studies
Chemotherapy
Chondrosarcoma
Chondrosarcoma, Mesenchymal - diagnosis
Chondrosarcoma, Mesenchymal - drug therapy
Chondrosarcoma, Mesenchymal - radiotherapy
Combined Modality Therapy
Diagnosis
Fatal Outcome
Head and neck tumors, mesenchymal chondrosarcoma, prognosis
Health aspects
Humans
Male
Mandibular Neoplasms - diagnosis
Mandibular Neoplasms - drug therapy
Mandibular Neoplasms - radiotherapy
Maxilla - pathology
Neoplasm Invasiveness
Palliative Care
Radiation therapy
Radiography
Radiotherapy
Spinal Neoplasms - diagnostic imaging
Surgery
Thoracic Vertebrae - diagnostic imaging
Tumors
Citations: Items that cite this one
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Summary:A 34-year-old man presented with an expansile, erosive tumor involving the left side of the mandible, with secondary invasion into the maxilla, measuring 13 Χ 7 cm. Microscopic analysis revealed a malignant small round cell neoplasm with focal cartilaginous differentiation. Immunohistochemical analysis revealed positivity for vimentin, NSE and CD99 with primitive small round cells, and S100 positivity with neoplastic chondrocytes. To the best of our knowledge, this is perhaps the largest reported case of mesenchymal chondrosarcoma of the maxillofacial region. Diagnosed as inoperable, he was treated with radiation and chemotherapy only to die within a few months.
ISSN:0973-1482
1998-4138
DOI:10.4103/0973-1482.82919