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Base catalyzed multicomponent synthesis of spiroheterocycles with fused heterosystems

Structurally diverse spiroheterocycles incorporating medicinally privileged heterosystems have been synthesized by a simple and convenient synthesis involving triethylamine catalyzed multicomponent domino reaction of 2-aminobenzothiazoles with isatin and cyclic 1,3-diketones.

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Bibliographic Details
Published in:Molecular diversity 2011-08, Vol.15 (3), p.781-789
Main Authors: Arya, Anand Kumar, Kumar, Mahendra
Format: Article
Language:English
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Summary:Structurally diverse spiroheterocycles incorporating medicinally privileged heterosystems have been synthesized by a simple and convenient synthesis involving triethylamine catalyzed multicomponent domino reaction of 2-aminobenzothiazoles with isatin and cyclic 1,3-diketones.
ISSN:1381-1991
1573-501X
DOI:10.1007/s11030-011-9309-2