Propanol as an end product of threonine fermentation

Clostridium sp. strain 17cr1 was able to ferment L-threonine to propionate and propanol. Electrons arising in the oxidation of 2-oxobutyrate to propionyl-CoA were apparently used in reductive pathway leading to propanol formation. Part of the propionyl-CoA was used to form propionate in an ATP-formi...

Full description

Saved in:
Bibliographic Details
Published in:Archives of microbiology 2004-12, Vol.182 (6), p.482-486
Main Author: JANSSEN, Peter H
Format: Article
Language:English
Subjects:
1-Propanol - metabolism
ATP
Biological and medical sciences
Clostridium
Clostridium - metabolism
Fermentation
Fundamental and applied biological sciences. Psychology
Microbiology
Species Specificity
Threonine - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Clostridium sp. strain 17cr1 was able to ferment L-threonine to propionate and propanol. Electrons arising in the oxidation of 2-oxobutyrate to propionyl-CoA were apparently used in reductive pathway leading to propanol formation. Part of the propionyl-CoA was used to form propionate in an ATP-forming pathway via a propionate kinase, so that the final ATP yield was 0.5 mol per mol of L-threonine metabolised. Other growth substrates were fermented mainly to acetate and butyrate, and the reductive formation of butyrate, from 2 mol of acetyl-CoA or from crotonate or 3-hydroxybutyrate, was the main route for recycling reduced electron carriers arising during oxidative pathways for most substrates.
ISSN:0302-8933
1432-072X
DOI:10.1007/s00203-004-0732-y