Air pollutants: The key stages in the pathway towards the development of cardiovascular disorders

Abstract Air pollution has been one of the significant risks to human health. Various studies indicate that ambient particulate matter in air pollution is most strongly allied to increased morbidity and mortality due to their link with cardiovascular adverse events. The mechanisms leading to these h...

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Bibliographic Details
Published in:Environmental toxicology and pharmacology 2011-01, Vol.31 (1), p.1-9
Main Authors: Shrey, Kohli, Suchit, Ahuja, Deepika, Dogra, Shruti, Krishnan, Vibha, Rani
Format: Article
Language:English
Subjects:
Air Pollutants - adverse effects
Air pollution
Animals
Atherosclerosis - chemically induced
Autonomic Nervous System - drug effects
Cardiomegaly - chemically induced
Cardiovascular Diseases - chemically induced
Cardiovascular Diseases - mortality
Cardiovascular Diseases - pathology
Cardiovascular event
Emergency
Heart
Humans
Inflammation
Myocardial Infarction - chemically induced
Oxidative Stress - drug effects
Particulate matter
Pollutants
Thrombosis - chemically induced
Vascular Diseases - chemically induced
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Summary:Abstract Air pollution has been one of the significant risks to human health. Various studies indicate that ambient particulate matter in air pollution is most strongly allied to increased morbidity and mortality due to their link with cardiovascular adverse events. The mechanisms leading to these harmful effects on the cardiovascular system have not been defined clearly but several hypotheses have been proposed that elucidate the direct and indirect effects of air pollution. Adverse cardiovascular events such as thrombosis, vascular dysfunction, atherosclerosis, myocardial infarction and disturbance in cardiac autonomic control are thought to be linked with air pollution. Recently, an association has also been found between cardiac hypertrophy and air pollution. The present review focuses on highlighting the implications of air pollution in deteriorating cardiac health.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2010.09.002