Metabolic health, obesity and 9-year incidence of peripheral arterial disease: The D.E.S.I.R. study

Abstract Objective To determine which metabolic and cardiovascular risk factors are associated with the change in ankle brachial pressure index and incident peripheral arterial disease over 9 years, and whether these associations differ between healthy weight and overweight & obese individuals....

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Bibliographic Details
Published in:Atherosclerosis 2011-06, Vol.216 (2), p.471-476
Main Authors: Skilton, Michael R, Chin-Dusting, Jaye P.F, Dart, Anthony M, Brazionis, Laima, Lantieri, Olivier, O’Dea, Kerin, Balkau, Beverley
Format: Article
Language:English
Subjects:
Adult
Aged
Ankle - pathology
Ankle Brachial Index
atherosclerosis
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
body mass index
Body Weight
Cardiology. Vascular system
Cardiovascular
Cholesterol, HDL - metabolism
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
fasting
Female
glucose
high density lipoprotein cholesterol
Humans
insulin
Insulin - blood
Insulin resistance
Male
Medical sciences
Metabolic syndrome
Middle Aged
Obesity
Obesity - complications
Overweight
Peripheral arterial disease
Peripheral Arterial Disease - complications
Peripheral Arterial Disease - diagnosis
Peripheral Arterial Disease - epidemiology
Principal Component Analysis
risk
risk factors
systolic blood pressure
triacylglycerols
Triglycerides - metabolism
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Summary:Abstract Objective To determine which metabolic and cardiovascular risk factors are associated with the change in ankle brachial pressure index and incident peripheral arterial disease over 9 years, and whether these associations differ between healthy weight and overweight & obese individuals. Methods Metabolic factors, change in ankle brachial pressure index and incidence of peripheral arterial disease (ankle brachial pressure index
ISSN:0021-9150
1879-1484
DOI:10.1016/j.atherosclerosis.2011.02.032