Multidimensional alcohol craving scale and [123Iiodobenzamide SPECT as predictors of early relapse in alcohol-dependent patients

The Multidimensional Alcohol Craving Scale (MACS) and Single Photon Emission Computerized Tomography (SPECT) with (123)I-iodobenzamide ((123)I-IBZM) can be useful tools for assessing relapse risk in early recovery from alcohol-dependency. The aim of this study was to assess possible relationships be...

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Bibliographic Details
Published in:Adicciones (Palma de Mallorca) 2011, Vol.23 (2), p.157-164
Main Authors: Guardia-Serecigni, Josep, Estorch, Montserrat, Surkov, Sergey, del Valle Camacho, M, García-Ribas, Guillermo
Format: Article
Language:Spanish
Subjects:
Adult
Alcoholism - diagnostic imaging
Alcoholism - psychology
Humans
Iodobenzenes
Male
Middle Aged
Predictive Value of Tests
Recurrence
Severity of Illness Index
Time Factors
Tomography, Emission-Computed, Single-Photon
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Summary:The Multidimensional Alcohol Craving Scale (MACS) and Single Photon Emission Computerized Tomography (SPECT) with (123)I-iodobenzamide ((123)I-IBZM) can be useful tools for assessing relapse risk in early recovery from alcohol-dependency. The aim of this study was to assess possible relationships between MACS score, (123)I-IBZM binding and time to first heavy drinking day (TFHD) after detoxification treatment. Nineteen alcohol-dependent in-patients were evaluated by MACS scale and an 123I-IBZM-SPECT, performed following alcohol detoxification treatment. At discharge, participants were advised to take naltrexone 50 mg/day for relapse prevention. TFHD was assessed over a 12-week follow up. The MACS score at the beginning of the detoxification process and naltrexone treatment after detoxification were independent predictive factors for TFHD. The MACS scale is a better predictor of TFHD than IBZM binding. It is simple, non-invasive and inexpensive and appears to be a useful instrument both for clinical practice and for research.
ISSN:0214-4840