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Identification and Imaging of the Nerves Responsible for Erectile Function in Rat Prostate, In Vivo, Using Optical Nerve Stimulation and Optical Coherence Tomography
The cavernous nerves on the prostate surface are responsible for erectile function. Optical diagnostic tools such as optical coherence tomography and laser nerve stimulation may assist in the identification, imaging, and preservation of these microscopic nerves during prostate cancer surgery, and th...
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Published in: | IEEE journal of selected topics in quantum electronics 2007-11, Vol.13 (6), p.1641-1645 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The cavernous nerves on the prostate surface are responsible for erectile function. Optical diagnostic tools such as optical coherence tomography and laser nerve stimulation may assist in the identification, imaging, and preservation of these microscopic nerves during prostate cancer surgery, and thus, help preserve sexual function after surgery. The feasibility of noncontact laser stimulation of the cavernous nerves is demonstrated in an in vivo rat prostate model with comparison to conventional electrical nerve stimulation. High-resolution optical coherence tomographic images of the nerves are also obtained and compared with histology. These optical technologies may be suitable as surgical guidance tools during laparoscopic and robotic nerve-sparing prostate cancer surgery. |
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ISSN: | 1077-260X 1558-4542 |
DOI: | 10.1109/JSTQE.2007.910119 |