Prevalence and risk factors for gastroesophageal reflux in pregnancy

Background and aim Prevalence of gastroesophageal reflux (GER) increases during pregnancy, due to several factors like decreased lower esophageal sphincter pressure, increased intra-abdominal pressure secondary to the enlarged gravid uterus and alteration in gastrointestinal transit. The present stu...

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Bibliographic Details
Published in:Indian journal of gastroenterology 2011-05, Vol.30 (3), p.144-147
Main Authors: Ramu, Bhavadharini, Mohan, Pazhanivel, Rajasekaran, Muthu Subramanian, Jayanthi, Venkataraman
Format: Article
Language:English
Subjects:
Adult
Case-Control Studies
Female
Gastroenterology
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - epidemiology
Heartburn - etiology
Hepatology
Humans
India - epidemiology
Laryngopharyngeal Reflux - etiology
Medicine
Medicine & Public Health
Original Article
Pregnancy
Pregnancy Complications
Pregnancy Trimesters
Prevalence
Risk Factors
Surveys and Questionnaires
Young Adult
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Summary:Background and aim Prevalence of gastroesophageal reflux (GER) increases during pregnancy, due to several factors like decreased lower esophageal sphincter pressure, increased intra-abdominal pressure secondary to the enlarged gravid uterus and alteration in gastrointestinal transit. The present study aimed to determine the prevalence of GER in pregnancy in a southern State of the Indian subcontinent and determine the risk factors associated with it. Methods Consecutive pregnant females ( n  = 400) at various stages of pregnancy attending the antenatal clinic or admitted in the antenatal wards were enrolled. Patients with heartburn or regurgitation or both ( n  = 182) for at least a week were defined as cases, and controls were those without these symptoms ( n  = 218). Data on demographic variables and symptoms were analyzed using Pearson chi-square, Yates corrected chi-square and Fischer exact test and student independent t -test as appropriate; p  
ISSN:0254-8860
0975-0711
DOI:10.1007/s12664-010-0067-3