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Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy

Abstract We herein describe a case of successful surgical treatment of isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogen...

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Published in:The American journal of surgery 2011-08, Vol.202 (2), p.e17-e19
Main Authors: Adachi, Kensuke, M.D, Ui, Mitsuhito, M.D, Nojima, Hiroyuki, M.D, Takada, Yukari, M.D, Enatsu, Kazuaki, M.D
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cites cdi_FETCH-LOGICAL-c447t-c61e7030423bfc05a3c2f9ff363a92aaf29f57ce2283ceed684ad7b53e8d27ae3
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container_title The American journal of surgery
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creator Adachi, Kensuke, M.D
Ui, Mitsuhito, M.D
Nojima, Hiroyuki, M.D
Takada, Yukari, M.D
Enatsu, Kazuaki, M.D
description Abstract We herein describe a case of successful surgical treatment of isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. To our knowledge, this is the first report in English of a case like this.
doi_str_mv 10.1016/j.amjsurg.2010.10.002
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Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. 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subjects Amyloidosis - diagnosis
Amyloidosis - etiology
Biomarkers - blood
Coagulation
Cysts - diagnostic imaging
Cysts - surgery
Disseminated intravascular coagulation
Disseminated Intravascular Coagulation - blood
Disseminated Intravascular Coagulation - etiology
Humans
Lesions
Male
Middle Aged
Organ Size
Pathogenesis
Pathology
Peliosis
Purpura - etiology
Severity of Illness Index
Spleen
Spleen - diagnostic imaging
Spleen - pathology
Spleen - surgery
Splenectomy
Splenic Diseases - blood
Splenic Diseases - complications
Splenic Diseases - diagnosis
Splenic Diseases - pathology
Splenic Diseases - surgery
Splenic peliosis
Splenomegaly
Splenomegaly - blood
Splenomegaly - etiology
Surgery
Tomography, X-Ray Computed
Treatment Outcome
title Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy
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