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Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy
Abstract We herein describe a case of successful surgical treatment of isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogen...
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Published in: | The American journal of surgery 2011-08, Vol.202 (2), p.e17-e19 |
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container_end_page | e19 |
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container_title | The American journal of surgery |
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creator | Adachi, Kensuke, M.D Ui, Mitsuhito, M.D Nojima, Hiroyuki, M.D Takada, Yukari, M.D Enatsu, Kazuaki, M.D |
description | Abstract We herein describe a case of successful surgical treatment of isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. To our knowledge, this is the first report in English of a case like this. |
doi_str_mv | 10.1016/j.amjsurg.2010.10.002 |
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Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. To our knowledge, this is the first report in English of a case like this.</description><identifier>ISSN: 0002-9610</identifier><identifier>EISSN: 1879-1883</identifier><identifier>DOI: 10.1016/j.amjsurg.2010.10.002</identifier><identifier>PMID: 21810495</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Amyloidosis - diagnosis ; Amyloidosis - etiology ; Biomarkers - blood ; Coagulation ; Cysts - diagnostic imaging ; Cysts - surgery ; Disseminated intravascular coagulation ; Disseminated Intravascular Coagulation - blood ; Disseminated Intravascular Coagulation - etiology ; Humans ; Lesions ; Male ; Middle Aged ; Organ Size ; Pathogenesis ; Pathology ; Peliosis ; Purpura - etiology ; Severity of Illness Index ; Spleen ; Spleen - diagnostic imaging ; Spleen - pathology ; Spleen - surgery ; Splenectomy ; Splenic Diseases - blood ; Splenic Diseases - complications ; Splenic Diseases - diagnosis ; Splenic Diseases - pathology ; Splenic Diseases - surgery ; Splenic peliosis ; Splenomegaly ; Splenomegaly - blood ; Splenomegaly - etiology ; Surgery ; Tomography, X-Ray Computed ; Treatment Outcome</subject><ispartof>The American journal of surgery, 2011-08, Vol.202 (2), p.e17-e19</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Aug 1, 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-c61e7030423bfc05a3c2f9ff363a92aaf29f57ce2283ceed684ad7b53e8d27ae3</citedby><cites>FETCH-LOGICAL-c447t-c61e7030423bfc05a3c2f9ff363a92aaf29f57ce2283ceed684ad7b53e8d27ae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21810495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Adachi, Kensuke, M.D</creatorcontrib><creatorcontrib>Ui, Mitsuhito, M.D</creatorcontrib><creatorcontrib>Nojima, Hiroyuki, M.D</creatorcontrib><creatorcontrib>Takada, Yukari, M.D</creatorcontrib><creatorcontrib>Enatsu, Kazuaki, M.D</creatorcontrib><title>Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy</title><title>The American journal of surgery</title><addtitle>Am J Surg</addtitle><description>Abstract We herein describe a case of successful surgical treatment of isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. 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Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. To our knowledge, this is the first report in English of a case like this.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>21810495</pmid><doi>10.1016/j.amjsurg.2010.10.002</doi></addata></record> |
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subjects | Amyloidosis - diagnosis Amyloidosis - etiology Biomarkers - blood Coagulation Cysts - diagnostic imaging Cysts - surgery Disseminated intravascular coagulation Disseminated Intravascular Coagulation - blood Disseminated Intravascular Coagulation - etiology Humans Lesions Male Middle Aged Organ Size Pathogenesis Pathology Peliosis Purpura - etiology Severity of Illness Index Spleen Spleen - diagnostic imaging Spleen - pathology Spleen - surgery Splenectomy Splenic Diseases - blood Splenic Diseases - complications Splenic Diseases - diagnosis Splenic Diseases - pathology Splenic Diseases - surgery Splenic peliosis Splenomegaly Splenomegaly - blood Splenomegaly - etiology Surgery Tomography, X-Ray Computed Treatment Outcome |
title | Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy |
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