A case of lupus-associated pancreatitis with ruptured pseudoaneurysms

Pancreatitis is a relatively rare complication in systemic lupus erythematosus (SLE). Herein we report a case of SLE with the initial development of acute pancreatitis, subsequently complicated by bleeding pseudoaneurysms. A 55-year-old Japanese woman was admitted to our hospital for the treatment o...

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Bibliographic Details
Published in:Modern rheumatology 2011-08, Vol.21 (4), p.428-431
Main Authors: Koga, Tomohiro, Miyashita, Taiichiro, Koga, Megumi, Izumi, Yasumori, Onizuka, Shinya, Fujioka, Hikaru, Fujiwara, Shinsuke, Nakamichi, Chikaaki, Nakashima, Kazuaki, Migita, Kiyoshi
Format: Article
Language:English
Subjects:
Aneurysm, False - diagnosis
Aneurysm, False - etiology
Aneurysm, False - therapy
Aneurysm, Ruptured - diagnosis
Aneurysm, Ruptured - etiology
Aneurysm, Ruptured - therapy
Aneurysms
Angiography
Anti-Bacterial Agents - therapeutic use
Case management
Case Report
Cysts
Embolization, Therapeutic
Female
Hemorrhage
Humans
Lupus
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - diagnosis
Lupus Erythematosus, Systemic - drug therapy
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Middle Aged
Orthopedics
Pancreas
Pancreatitis - diagnosis
Pancreatitis - drug therapy
Pancreatitis - etiology
Prednisolone - administration & dosage
Rheumatology
Splenic Artery
Tomography, X-Ray Computed
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Description
Summary:Pancreatitis is a relatively rare complication in systemic lupus erythematosus (SLE). Herein we report a case of SLE with the initial development of acute pancreatitis, subsequently complicated by bleeding pseudoaneurysms. A 55-year-old Japanese woman was admitted to our hospital for the treatment of SLE. During the course of treatment, she complained of upper abdominal pain. An abdominal computed tomography (CT) scan showed that the pancreas was diffusely enlarged, and she was diagnosed with acute pancreatitis. Her pancreatitis was resistant to glucocorticoid therapy and was subsequently associated with pancreatic pseudocysts and recurrent rupture of the pseudoaneurysms. After surgical drainage of the hemorrhagic pseudocysts, the patient’s clinical condition gradually improved with intensive therapies. Our case indicates that lupus pancreatitis can be associated with the potentially fatal complication of recurrent bleeding of pseudoaneurysms.
ISSN:1439-7595
1439-7609
DOI:10.1007/s10165-011-0415-x