Beneficial effects of banana (Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats

• Published in: Journal of physiology and biochemistry 2011-09, Vol.67 (3), p.415-425
• Main Authors: Bhaskar, Jamuna J., Shobha, Mysore S., Sambaiah, Kari, Salimath, Paramahans V.
• Format: Article
• Language: English
• Subjects: Animal Physiology; Animals; Biomedical and Life Sciences; Biomedicine; Blood Glucose; Body Weight; Carbohydrates - urine; Diabetes Mellitus, Experimental - diet therapy; Diabetes Mellitus, Experimental - metabolism; Drinking; Energy Intake; Flowers; Fructosamine - blood; Fructosamine - metabolism; Glycation End Products, Advanced - blood; Glycation End Products, Advanced - metabolism; Glycemic Index; Human Physiology; Hyperglycemia - diet therapy; Kidney - metabolism; Liver - metabolism; Musa; Original Paper; Plant Stems; Rats; Rats, Wistar; Streptozocin
• ISSN: 1138-7548; 1877-8755
• DOI: 10.1007/s13105-011-0091-5

Diabetes is a chronic health problem and major cause of death in most of the countries. Diet management plays an important role in controlling diabetes and its complications along with insulin and drugs. We have examined the effect of banana ( Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats. Our results indicated that banana flower and pseudostem have low glycemic index and have a high content of dietary fiber and antioxidants. Diabetic symptoms like hyperglycemia, polyuria, polyphagia, polydipsia, urine sugar, and body weight were ameliorated in banana flower- and pseudostem-treated rats. Increased glomerular filtration rate in the diabetic group (5.1 ± 0.22 ml/min) was decreased in banana flower-fed (2.5 ± 0.37 ml/min) and pseudostem-fed (3.0 ± 0.45 ml/min) groups and were significant at P