In vitro colonization of an experimental silicone by Candida albicans

Denture soft‐lining materials are exposed to the oral cavity for long periods and are in continuous contact with saliva, subject to inhibition of liquid molecules, and susceptible to colonization by microorganisms. The opportunist yeast Candida albicans is of particular concern in this context, bein...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2010-01, Vol.92B (1), p.226-235
Main Authors: Rodger, Gillian, Taylor, Rebecca L., Pearson, Gavin J., Verran, Joanna
Format: Article
Language:English
Subjects:
adhesion
Bacteria
Bacteria - isolation & purification
bacterial adherence
Biofilms
Biological and medical sciences
Candida
Candida albicans
Candida albicans - growth & development
Candida albicans - isolation & purification
Colony Count, Microbial
Culture
Dental materials
dental/craniofacial material
Dentures
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Humans
In Vitro Techniques
Maxillofacial surgery. Dental surgery. Orthodontics
Medical sciences
Models, Theoretical
Penetration
polymer
Prosthetics
silicone/PDMS
Silicones
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgical implants
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Denture soft‐lining materials are exposed to the oral cavity for long periods and are in continuous contact with saliva, subject to inhibition of liquid molecules, and susceptible to colonization by microorganisms. The opportunist yeast Candida albicans is of particular concern in this context, being associated with denture plaque and denture‐related stomatitis. In this study, penetration of C. albicans into an experimental silicone elastomer soft‐lining material was investigated under batch and continuous culture conditions. A model “denture plaque“ microcosm was also used. Increasing the filler concentration within the elastomer decreased penetration under both batch and continuous culture conditions. In continuous culture, C. albicans penetration was significantly greater in pure culture than in the presence of bacteria after 72‐h incubation (p < 0.05). © 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010
ISSN:1552-4973
1552-4981
1552-4981
DOI:10.1002/jbm.b.31509