Soft tissue adaptation to modified titanium surfaces

Surface modification of titanium alloy implants to enhance soft tissue adherence is important to minimize soft tissue dehiscence. This study aimed to confirm if a dual acid etched “Osseotite®” titanium surface contributes to soft tissue adherence in muscle. It also aims to explore if a radio frequen...

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Bibliographic Details
Published in:Journal of biomedical materials research. Part A 2010-11, Vol.95A (2), p.543-549
Main Authors: Lee, Shermin, Goh, Bee Tin, Wolke, Joop, Tideman, Henk, Stoelinga, Paul, Jansen, John
Format: Article
Language:English
Subjects:
Animals
bioglass
Biological and medical sciences
Ceramics - chemistry
Coated Materials, Biocompatible - chemistry
Coated Materials, Biocompatible - metabolism
Durapatite - chemistry
Macaca fascicularis
Male
Materials Testing
Medical sciences
Muscles - anatomy & histology
Muscles - metabolism
Osseotite
soft tissue
Surface Properties
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technology. Biomaterials. Equipments
Titanium - chemistry
titanium alloy
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Summary:Surface modification of titanium alloy implants to enhance soft tissue adherence is important to minimize soft tissue dehiscence. This study aimed to confirm if a dual acid etched “Osseotite®” titanium surface contributes to soft tissue adherence in muscle. It also aims to explore if a radio frequency magnetron sputtered hydroxyapatite (HA)/bioglass (BG) coating can serve this purpose and provides soft tissue adherence in mucosal tissue. The study was carried out in 18 Macaca fascicularis animals, 14 Osseotite® coated Ti6Al4V bullets inserted intramuscularly and 12 HA/BG coated Ti6Al4V plates inserted into the submucosa. These were compared with machined Ti6Al4V surfaces as controls. The histological and histomorphometrical results revealed that no significant difference existed in muscle tissue response between machined and Osseotite® surfaces. On the other hand, the HA/BG coated submucosal plates showed statistically significant differences with a thinner capsule quantity (p < 0.0001), an increased capsule quality (p < 0.0001) and interface quality score (p < 0.05). In conclusion, the deposited HA/BG coatings facilitated soft tissue (mucosa) adaptation at 1 month of implant installation, whereas the acid etched Osseotite® surface did not enhance muscular adaptation. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
ISSN:1549-3296
1552-4965
1552-4965
DOI:10.1002/jbm.a.32849