Intraneural perineurioma

Abstract Intraneural perineurioma is a rare tumour that affects peripheral nerves and, based on its histological features, may be confused with hereditary motor and sensory neuropathies. Detailed neuropathology, including immunoperoxidase stains and electron microscopy, is vital to distinguish these...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical neuroscience 2009-12, Vol.16 (12), p.1633-1636
Main Authors: Lee, H.-Y, Manasseh, R.G, Edis, R.H, Page, R, Keith-Rokosh, J, Walsh, P, Song, S, Laycock, A, Griffiths, L, Fabian, V.A
Format: Article
Language:English
Subjects:
Adolescent
Child
Female
Humans
Intraneural perineurioma
Magnetic Resonance Imaging - methods
Male
Management
Microscopy, Electron, Transmission - methods
Nerve
Nerve grafting
Nerve Sheath Neoplasms - diagnosis
Neurology
Neuropathology
Peripheral Nerves - pathology
Peripheral Nerves - surgery
Peripheral Nerves - ultrastructure
Peripheral Nervous System Neoplasms - diagnosis
Peripheral Nervous System Neoplasms - surgery
Pseudo-onion bulbs
Sural Nerve - transplantation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Intraneural perineurioma is a rare tumour that affects peripheral nerves and, based on its histological features, may be confused with hereditary motor and sensory neuropathies. Detailed neuropathology, including immunoperoxidase stains and electron microscopy, is vital to distinguish these conditions. We report two patients with intraneural perineurioma that demonstrate salient features of this tumour. The first patient is the longest reported follow-up of an intraneural perineurioma; extension of the lesion was observed over 14 years. The second patient is an 11-year-old female whose treatment highlights some of the controversy surrounding the management of these lesions, and the importance of thorough macroscopic and microscopic assessment by pathologists, including the status of surgical resection margins.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2009.02.013