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Mortality in Individuals With Autism, With and Without Epilepsy
Previous studies show higher mortality rates among individuals with autism than the general population. Comorbidity with epilepsy is an assumed, often ill-defined factor in the increased mortality rates of individuals with autism. Data from the Autism Tissue Program, a tissue donation program establ...
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Published in: | Journal of Child Neurology 2011-08, Vol.26 (8), p.932-939 |
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container_title | Journal of Child Neurology |
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creator | Pickett, Jane Xiu, Ellen Tuchman, Roberto Dawson, Geraldine Lajonchere, Clara |
description | Previous studies show higher mortality rates among individuals with autism than the general population. Comorbidity with epilepsy is an assumed, often ill-defined factor in the increased mortality rates of individuals with autism. Data from the Autism Tissue Program, a tissue donation program established to support biomedical research on autism, show that approximately one-third of its brain donors with autism also had epilepsy. Analysis of new data from the California State Department of Developmental Services is consistent with past reports showing that there is a higher than expected rate of mortality in individuals with autism and epilepsy than autism alone. Accurate, complete and accessible records on cause of death are necessary not just for brain research, but also for understanding risk factors that contribute to early death in individuals with autism spectrum disorders. Various national health care and state developmental disability agency initiatives to reduce risk of mortality are described. |
doi_str_mv | 10.1177/0883073811402203 |
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Comorbidity with epilepsy is an assumed, often ill-defined factor in the increased mortality rates of individuals with autism. Data from the Autism Tissue Program, a tissue donation program established to support biomedical research on autism, show that approximately one-third of its brain donors with autism also had epilepsy. Analysis of new data from the California State Department of Developmental Services is consistent with past reports showing that there is a higher than expected rate of mortality in individuals with autism and epilepsy than autism alone. Accurate, complete and accessible records on cause of death are necessary not just for brain research, but also for understanding risk factors that contribute to early death in individuals with autism spectrum disorders. 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Various national health care and state developmental disability agency initiatives to reduce risk of mortality are described.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Autistic Disorder - mortality</subject><subject>California - epidemiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Comorbidity</subject><subject>Epilepsy - mortality</subject><subject>Female</subject><subject>Humans</subject><subject>Individuality</subject><subject>Infant</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Risk Factors</subject><subject>Young Adult</subject><issn>0883-0738</issn><issn>1708-8283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqFkE1LxDAQhoMo7rp69yS9ebE6-WriSZZl1YUVL4rHkCapZumXTSvsv7fdqgdBPM0M88zL8CB0iuESYyGuQEoKgkqMGRACdA9NsQAZSyLpPpoO63jYT9BRCBsAkPwaDtGEYCYw53iKbh6qptW5b7eRL6NVaf2Ht53OQ_Ti27do3rU-FBfjoEu7a6qujZa1z10dtsfoIOtpd_JVZ-j5dvm0uI_Xj3erxXwdG5rINjaCO8upE5AML7PEGsEISZjTkrgUE8BCJtyk2tLMZpTplHNGsZPWZNaldIbOx9y6qd47F1pV-GBcnuvSVV1Qu1SRAPufFFJiKXpDMwQjaZoqhMZlqm58oZutwqAGv-q33_7k7Cu8Swtnfw6-hfZAPAJBvzq1qbqm7LX8HfgJtAOA7g</recordid><startdate>201108</startdate><enddate>201108</enddate><creator>Pickett, Jane</creator><creator>Xiu, Ellen</creator><creator>Tuchman, Roberto</creator><creator>Dawson, Geraldine</creator><creator>Lajonchere, Clara</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>201108</creationdate><title>Mortality in Individuals With Autism, With and Without Epilepsy</title><author>Pickett, Jane ; Xiu, Ellen ; Tuchman, Roberto ; Dawson, Geraldine ; Lajonchere, Clara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c368t-c75ed53e706883046dc742264ea82eb12017865cbad3fdf34ab55431e8dcfdeb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Autistic Disorder - mortality</topic><topic>California - epidemiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Comorbidity</topic><topic>Epilepsy - mortality</topic><topic>Female</topic><topic>Humans</topic><topic>Individuality</topic><topic>Infant</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Risk Factors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pickett, Jane</creatorcontrib><creatorcontrib>Xiu, Ellen</creatorcontrib><creatorcontrib>Tuchman, Roberto</creatorcontrib><creatorcontrib>Dawson, Geraldine</creatorcontrib><creatorcontrib>Lajonchere, Clara</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Journal of Child Neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pickett, Jane</au><au>Xiu, Ellen</au><au>Tuchman, Roberto</au><au>Dawson, Geraldine</au><au>Lajonchere, Clara</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mortality in Individuals With Autism, With and Without Epilepsy</atitle><jtitle>Journal of Child Neurology</jtitle><addtitle>J Child Neurol</addtitle><date>2011-08</date><risdate>2011</risdate><volume>26</volume><issue>8</issue><spage>932</spage><epage>939</epage><pages>932-939</pages><issn>0883-0738</issn><eissn>1708-8283</eissn><abstract>Previous studies show higher mortality rates among individuals with autism than the general population. 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subjects | Adolescent Adult Age Factors Autistic Disorder - mortality California - epidemiology Child Child, Preschool Comorbidity Epilepsy - mortality Female Humans Individuality Infant Male Middle Aged Risk Factors Young Adult |
title | Mortality in Individuals With Autism, With and Without Epilepsy |
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