Presenile dementia: a case of Hashimoto's encephalopathy

Hashimoto's encephalopathy may present with a variety of neurological symptoms and signs, including myoclonus, epileptic seizures, disturbance of consciousness, psychosis, ataxia, and presenile dementia. This report is of a 57-year-old woman with a history of thyroid disease who was investigate...

Full description

Saved in:
Bibliographic Details
Published in:East Asian archives of psychiatry 2011-03, Vol.21 (1), p.32-36
Main Authors: Chong, C S Y, Leung, J L M, Wong, I H H, Ng, P W, Miao, M Y K
Format: Article
Language:English
Subjects:
Activities of daily living
Alzheimer Disease - diagnosis
Alzheimer Disease - etiology
Alzheimer's disease
Antibodies
Atrophy
Brain - diagnostic imaging
Brain - pathology
Brain Diseases - complications
Brain Diseases - diagnosis
Brain Diseases - drug therapy
Care and treatment
Case reports
Case studies
Cognitive ability
Convulsions & seizures
Creutzfeldt-Jakob disease
Dementia
Diagnosis
Diagnosis, Differential
Diseases
Drug therapy
Encephalitis
Encephalomyelitis
Encephalopathy
Family medical history
Female
Glucocorticoids - therapeutic use
Hashimoto Disease - complications
Hashimoto Disease - diagnosis
Hashimoto Disease - drug therapy
Health aspects
Humans
Illnesses
Immunoglobulins
Magnetic Resonance Imaging
Middle Aged
Pathogenesis
Patients
Pediatrics
Prednisolone
Prednisolone - therapeutic use
Presenile dementia
Risk factors
Steroids
Thyroid diseases
Thyroid Diseases - complications
Thyroid gland
Tomography, X-Ray Computed
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hashimoto's encephalopathy may present with a variety of neurological symptoms and signs, including myoclonus, epileptic seizures, disturbance of consciousness, psychosis, ataxia, and presenile dementia. This report is of a 57-year-old woman with a history of thyroid disease who was investigated for generalised seizures, rapid decline in cognitive function, increasing dependency, and gradual change in personality. High thyroid autoantibody titres confirmed the diagnosis of Hashimoto's encephalopathy and her symptoms improved with treatment with prednisolone. The differential diagnosis of presenile dementia, aetiology and pathogenesis of Hashimoto's encephalomyelitis, and treatment options are discussed. Hashimoto's encephalomyelitis should be considered in the differential diagnosis of presenile dementia, particularly in patients with a history of thyroid disease.
ISSN:2078-9947
2224-7041