Human gut microbiota and its relationship to health and disease

Probiotics are live microorganisms that confer a health benefit on the host when administered in appropriate amounts. Over 700 randomized, controlled, human studies have been conducted with probiotics thus far, with the results providing strong support for the use of probiotics in the clinical preve...

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Bibliographic Details
Published in:Nutrition reviews 2011-07, Vol.69 (7), p.392-403
Main Authors: Wallace, Taylor C, Guarner, Francisco, Madsen, Karen, Cabana, Michael D, Gibson, Glenn, Hentges, Eric, Sanders, Mary Ellen
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
clinical guidelines
Clinical trials
Fundamental and applied biological sciences. Psychology
Gastroenterology
Gastrointestinal diseases
Gastrointestinal Diseases - diet therapy
Gastrointestinal Diseases - prevention & control
gut microbiota
health
Health Status
Humans
intervention
Intestine. Mesentery
Metabolic Syndrome - diet therapy
Metabolic Syndrome - prevention & control
Practice Guidelines as Topic
prebiotic
Prebiotics
probiotic
Probiotics
Probiotics - therapeutic use
Public health
Vertebrates: digestive system
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Summary:Probiotics are live microorganisms that confer a health benefit on the host when administered in appropriate amounts. Over 700 randomized, controlled, human studies have been conducted with probiotics thus far, with the results providing strong support for the use of probiotics in the clinical prevention or treatment of gastrointestinal tract disorders and metabolic syndrome. The present review is based on webinar presentations that were developed by the American Gastroenterological Association (AGA) in partnership with the International Scientific Association for Probiotics and Prebiotics (ISAPP) and the North American branch of the International Life Sciences Institute (ILSI North America). The presentations provided gastroenterologists and researchers with fundamental and current scientific information on the influence of gut microbiota on human health and disease, as well as clinical intervention strategies and practical guidelines for the use of probiotics and prebiotics.
ISSN:0029-6643
1753-4887
DOI:10.1111/j.1753-4887.2011.00402.x