Resection of lung metastases from hepatocellular carcinoma after living donor liver transplantation: Report of two cases

Hepatocellular carcinoma (HCC) recurrence after liver transplantation is associated with a poor prognosis; nonetheless, we report two cases of long-term survival after resection of pulmonary metastatic lesions following living donor liver transplantation (LDLT). The intervals between LDLT and pulmon...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2011-09, Vol.41 (9), p.1294-1297
Main Authors: Togashi, Junichi, Sugawara, Yasuhiko, Aoki, Taku, Tamura, Sumihito, Kaneko, Junichi, Nakajima, Jun, Sano, Atsushi, Kokudo, Norihiro
Format: Article
Language:English
Subjects:
Adult
Carcinoma, Hepatocellular - secondary
Carcinoma, Hepatocellular - surgery
Case Report
Disease-Free Survival
Humans
Liver Neoplasms - pathology
Liver Neoplasms - surgery
Liver Transplantation
Living Donors
Lung Neoplasms - secondary
Lung Neoplasms - surgery
Male
Medicine
Medicine & Public Health
Middle Aged
Pneumonectomy
Surgery
Surgical Oncology
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Summary:Hepatocellular carcinoma (HCC) recurrence after liver transplantation is associated with a poor prognosis; nonetheless, we report two cases of long-term survival after resection of pulmonary metastatic lesions following living donor liver transplantation (LDLT). The intervals between LDLT and pulmonary resection for the metastatic lesion were 24 months and 30 months, respectively. Regular checking of tumor markers and prompt workup for early detection may contribute to the resectability of such metastatic lesions. These cases suggest that resection of a solitary metastatic lesion in the lung from HCC after liver transplantation may be a feasible treatment for selected patients.
ISSN:0941-1291
1436-2813
DOI:10.1007/s00595-010-4487-6