Effect of Various Anticoagulant Agents on Large-Volume Leukocytapheresis Using New Cellsorba CS-180S Filter

We conducted a study to evaluate the effect of various anticoagulant agents on large‐volume leukocytapheresis using the new Cellsorba CS‐180S Filter filled with a changed solution of sodium pyrosulfite and sodium carbonate. We conducted the study on a total of 12 cases of rheumatoid arthritis. As th...

Full description

Saved in:
Bibliographic Details
Published in:Therapeutic apheresis and dialysis 2011-08, Vol.15 (4), p.355-359
Main Authors: Hohtatsu, Katsura, Yamaji, Ken, Yamada, Risa, Oda, Keisuke, Kageyama, Michiaki, Kusaoi, Makio, Onuma, Shin, Kawamoto, Toshio, Sugimoto, Kaoru, Sekiya, Fumio, Kon, Takayuki, Ogasawara, Michihiro, Kempe, Kazuo, Tsuda, Hiroshi, Takasaki, Yoshinari
Format: Article
Language:English
Subjects:
Anticoagulant agents
Anticoagulants - administration & dosage
Arthritis, Rheumatoid - therapy
Carbonates - chemistry
Citrates - administration & dosage
Filtration - instrumentation
Guanidines - administration & dosage
Heparin, Low-Molecular-Weight - administration & dosage
Humans
Leukapheresis - instrumentation
Leukapheresis - methods
Leukocytapheresis
Neutrophils - metabolism
New filter
Rheumatoid arthritis
Sodium pyrosulfite
Sulfites - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We conducted a study to evaluate the effect of various anticoagulant agents on large‐volume leukocytapheresis using the new Cellsorba CS‐180S Filter filled with a changed solution of sodium pyrosulfite and sodium carbonate. We conducted the study on a total of 12 cases of rheumatoid arthritis. As the anticoagulant agents we used sodium citrate, nafamostat mesilate and low molecular weight heparin. The new Cellsorba CS‐180S was safely used with the various blood anticoagulant agents. Also, through adjustment of the sodium citrate percentage to the blood flow volume, it is hypothesized that it is possible to increase the neutrophil removal rate.
ISSN:1744-9979
1744-9987
DOI:10.1111/j.1744-9987.2011.00962.x