Microsurgical management of prolactinomas - clinical and hormonal outcome in a series of 172 cases

To report hormonal outcome after surgery in a special subgroup of prolactinomas in whom medical therapy is not effective or not indicated. All patients who underwent surgery for prolactinomas, between December 2002 and December 2009, were analyzed retrospectively. The study group consisted of patien...

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Bibliographic Details
Published in:Neurology India 2011-07, Vol.59 (4), p.532-536
Main Authors: Sinha, Sumit, Sharma, B S, Mahapatra, A K
Format: Article
Language:English
Subjects:
Care and treatment
Case studies
Diagnosis
Endocrine glands
Female
Follow-Up Studies
Health aspects
Humans
Microsurgery - methods
Mortality
Pituitary gland
Pituitary Neoplasms - metabolism
Pituitary Neoplasms - surgery
Prolactin - metabolism
Prolactinoma
Prolactinoma - metabolism
Prolactinoma - surgery
Radiotherapy
Retrospective Studies
Surgery
Treatment Outcome
Tumors
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Summary:To report hormonal outcome after surgery in a special subgroup of prolactinomas in whom medical therapy is not effective or not indicated. All patients who underwent surgery for prolactinomas, between December 2002 and December 2009, were analyzed retrospectively. The study group consisted of patients who were either intolerant or noncompliant to dopamine agonist (DA) therapy or those in whom medical treatment could not be given due to various reasons. The surgical results were assessed according to whether patients had microadenoma (1 cm diameter), or giant prolactinoma (>4 cm diameter). Initial and final hormonal remission was defined as normalization of serum prolactin levels (
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.84332