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Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial

Background/Objectives: Hypoglycemic effect of camel milk supplementation in experimental rat model and significant reduction in doses of insulin in type 1 diabetic patients have been observed in our previous studies. This long-term study was undertaken to assess the efficacy, safety and acceptabilit...

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Published in:European journal of clinical nutrition 2011-09, Vol.65 (9), p.1048-1052
Main Authors: Agrawal, R P, Jain, S, Shah, S, Chopra, A, Agarwal, V
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description Background/Objectives: Hypoglycemic effect of camel milk supplementation in experimental rat model and significant reduction in doses of insulin in type 1 diabetic patients have been observed in our previous studies. This long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an adjunct to insulin therapy in type 1 diabetics. Subjects/Methods: In this 2-year randomized clinical, parallel design study, 24 type 1 diabetics were enrolled and divided into two groups. Group I ( n =12) received usual care, that is, diet, exercise and insulin and Group II ( n =12) received 500 ml camel milk in addition to the usual care. Insulin requirement was titrated weekly by blood glucose estimation. Results were analyzed by using the regression technique. Results: In camel milk group, there was decrease in mean blood glucose (118.58±19–93.16±17.06 mg/dl), hemoglobin A1c levels (7.81±1.39–5.44±0.81%) and insulin doses (32.50±9.99–17.50±12.09 U/day, P
doi_str_mv 10.1038/ejcn.2011.98
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subjects 692/699/2743/137/1418
692/700/565/2072
Adolescent
Adult
Animals
Antibodies
Biological and medical sciences
Blood
Blood glucose
Blood Glucose - analysis
Camel's milk
Camelus
Child
Clinical Nutrition
Clinical trials
Diabetes
Diabetes mellitus (insulin dependent)
Diabetes Mellitus, Type 1 - diet therapy
Diabetes Mellitus, Type 2 - diet therapy
Diabetes. Impaired glucose tolerance
Diabetics
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Epidemiology
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Feeding. Feeding behavior
Fundamental and applied biological sciences. Psychology
Glucose
Glycated Hemoglobin A - analysis
Glycoproteins
Health aspects
Hemoglobin
Humans
Hypoglycemic Agents - administration & dosage
Insulin
Insulin - blood
Insulin Antibodies - blood
Internal Medicine
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Milk
original-article
Patients
Physiological aspects
Public Health
Reduction
Type 1 diabetes
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Young Adult
title Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial
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