Gene Editing in Stem Cells Hits the Target

Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem cells using zinc finger nuclease (ZFN)-mediated (Soldner et al., 2011) or helper-dependent adenovirus (HDAdV)-mediated (Liu et al., 2011b) gene modification. These technical developments will have far...

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Bibliographic Details
Published in:Cell stem cell 2011-08, Vol.9 (2), p.93-94
Main Authors: Kim, Ho W., Svendsen, Clive Niels
Format: Article
Language:English
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Summary:Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem cells using zinc finger nuclease (ZFN)-mediated (Soldner et al., 2011) or helper-dependent adenovirus (HDAdV)-mediated (Liu et al., 2011b) gene modification. These technical developments will have far ranging effects on the rapidly growing field of regenerative medicine.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2011.07.011