Relationship between the clinical characteristics of osteomyelitis and the finding of extraosseous fat on MRI in pediatric patients

Background MRI is frequently utilized to evaluate patients for osteomyelitis. The findings of intramedullary and extramedullary fat globules as well as extramedullary fat-fluid levels can help improve the specificity of MRI for this diagnosis. Objective To correlate these MRI findings with the clini...

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Published in:Pediatric radiology 2011-10, Vol.41 (10), p.1293-1297
Main Authors: Mattis, Tod A., Borders, Heather L., Ellinger, Doug M., Junewick, Joseph J.
Format: Article
Language:English
Subjects:
Adipose Tissue - pathology
Adolescent
Child
Child, Preschool
Female
Humans
Imaging
Infant
Infant, Newborn
Magnetic Resonance Imaging - methods
Male
Medicine
Medicine & Public Health
Neuroradiology
Nuclear Medicine
Oncology
Original Article
Osteomyelitis - diagnosis
Osteomyelitis - pathology
Pediatrics
Radiology
Retrospective Studies
Sensitivity and Specificity
Statistics, Nonparametric
Ultrasound
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cited_by cdi_FETCH-LOGICAL-c371t-db4852d7b53a418be8e7927cf3170c0d83caf93270fc2c7890e86f90a843459c3
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container_end_page 1297
container_issue 10
container_start_page 1293
container_title Pediatric radiology
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creator Mattis, Tod A.
Borders, Heather L.
Ellinger, Doug M.
Junewick, Joseph J.
description Background MRI is frequently utilized to evaluate patients for osteomyelitis. The findings of intramedullary and extramedullary fat globules as well as extramedullary fat-fluid levels can help improve the specificity of MRI for this diagnosis. Objective To correlate these MRI findings with the clinical characteristics in children with osteomyelitis. Materials and methods A retrospective electronic medical record search for pediatric patient charts from March 2004 to November 2009 that contained the word “osteomyelitis” in the “principal diagnosis” portion of the international classification of disease (ICD) billing code. Each electronic chart was reviewed. MRI examinations of selected children were reviewed by a pediatric radiologist, a general radiologist and a transitional year resident. Results A total of 10 patients/11 MRI studies were included. Five of the 11 had the MRI finding of extramedullary globular fat signal. There was a significantly increased likelihood of seeing this finding in children of pubertal or postpubertal age compared to those of prepubertal age ( p  
doi_str_mv 10.1007/s00247-011-2073-8
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The findings of intramedullary and extramedullary fat globules as well as extramedullary fat-fluid levels can help improve the specificity of MRI for this diagnosis. Objective To correlate these MRI findings with the clinical characteristics in children with osteomyelitis. Materials and methods A retrospective electronic medical record search for pediatric patient charts from March 2004 to November 2009 that contained the word “osteomyelitis” in the “principal diagnosis” portion of the international classification of disease (ICD) billing code. Each electronic chart was reviewed. MRI examinations of selected children were reviewed by a pediatric radiologist, a general radiologist and a transitional year resident. Results A total of 10 patients/11 MRI studies were included. Five of the 11 had the MRI finding of extramedullary globular fat signal. There was a significantly increased likelihood of seeing this finding in children of pubertal or postpubertal age compared to those of prepubertal age ( p  &lt; 0.05). Conclusion This study provides evidence that the MRI finding of extramedullary fat globules in children with acute osteomyelitis is associated with the clinical characteristic of being within or above the age range for puberty.</description><identifier>ISSN: 0301-0449</identifier><identifier>EISSN: 1432-1998</identifier><identifier>DOI: 10.1007/s00247-011-2073-8</identifier><identifier>PMID: 21553040</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adipose Tissue - pathology ; Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Imaging ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging - methods ; Male ; Medicine ; Medicine &amp; Public Health ; Neuroradiology ; Nuclear Medicine ; Oncology ; Original Article ; Osteomyelitis - diagnosis ; Osteomyelitis - pathology ; Pediatrics ; Radiology ; Retrospective Studies ; Sensitivity and Specificity ; Statistics, Nonparametric ; Ultrasound</subject><ispartof>Pediatric radiology, 2011-10, Vol.41 (10), p.1293-1297</ispartof><rights>Springer-Verlag 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-db4852d7b53a418be8e7927cf3170c0d83caf93270fc2c7890e86f90a843459c3</citedby><cites>FETCH-LOGICAL-c371t-db4852d7b53a418be8e7927cf3170c0d83caf93270fc2c7890e86f90a843459c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21553040$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mattis, Tod A.</creatorcontrib><creatorcontrib>Borders, Heather L.</creatorcontrib><creatorcontrib>Ellinger, Doug M.</creatorcontrib><creatorcontrib>Junewick, Joseph J.</creatorcontrib><title>Relationship between the clinical characteristics of osteomyelitis and the finding of extraosseous fat on MRI in pediatric patients</title><title>Pediatric radiology</title><addtitle>Pediatr Radiol</addtitle><addtitle>Pediatr Radiol</addtitle><description>Background MRI is frequently utilized to evaluate patients for osteomyelitis. The findings of intramedullary and extramedullary fat globules as well as extramedullary fat-fluid levels can help improve the specificity of MRI for this diagnosis. Objective To correlate these MRI findings with the clinical characteristics in children with osteomyelitis. Materials and methods A retrospective electronic medical record search for pediatric patient charts from March 2004 to November 2009 that contained the word “osteomyelitis” in the “principal diagnosis” portion of the international classification of disease (ICD) billing code. Each electronic chart was reviewed. MRI examinations of selected children were reviewed by a pediatric radiologist, a general radiologist and a transitional year resident. Results A total of 10 patients/11 MRI studies were included. Five of the 11 had the MRI finding of extramedullary globular fat signal. There was a significantly increased likelihood of seeing this finding in children of pubertal or postpubertal age compared to those of prepubertal age ( p  &lt; 0.05). 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The findings of intramedullary and extramedullary fat globules as well as extramedullary fat-fluid levels can help improve the specificity of MRI for this diagnosis. Objective To correlate these MRI findings with the clinical characteristics in children with osteomyelitis. Materials and methods A retrospective electronic medical record search for pediatric patient charts from March 2004 to November 2009 that contained the word “osteomyelitis” in the “principal diagnosis” portion of the international classification of disease (ICD) billing code. Each electronic chart was reviewed. MRI examinations of selected children were reviewed by a pediatric radiologist, a general radiologist and a transitional year resident. Results A total of 10 patients/11 MRI studies were included. Five of the 11 had the MRI finding of extramedullary globular fat signal. There was a significantly increased likelihood of seeing this finding in children of pubertal or postpubertal age compared to those of prepubertal age ( p  &lt; 0.05). Conclusion This study provides evidence that the MRI finding of extramedullary fat globules in children with acute osteomyelitis is associated with the clinical characteristic of being within or above the age range for puberty.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>21553040</pmid><doi>10.1007/s00247-011-2073-8</doi><tpages>5</tpages></addata></record>
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ispartof Pediatric radiology, 2011-10, Vol.41 (10), p.1293-1297
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source Springer Nature
subjects Adipose Tissue - pathology
Adolescent
Child
Child, Preschool
Female
Humans
Imaging
Infant
Infant, Newborn
Magnetic Resonance Imaging - methods
Male
Medicine
Medicine & Public Health
Neuroradiology
Nuclear Medicine
Oncology
Original Article
Osteomyelitis - diagnosis
Osteomyelitis - pathology
Pediatrics
Radiology
Retrospective Studies
Sensitivity and Specificity
Statistics, Nonparametric
Ultrasound
title Relationship between the clinical characteristics of osteomyelitis and the finding of extraosseous fat on MRI in pediatric patients
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