Organic Electrochemical Transistors Integrated in Flexible Microfluidic Systems and Used for Label-Free DNA Sensing

Organic electrochemical transistors are integrated in flexible microfluidic systems. A novel label‐free DNA sensor is developed based on the devices with single‐stranded DNA probes immobilized on gate electrodes. These devices successfully detect complementary DNA targets at low concentrations using...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2011-09, Vol.23 (35), p.4035-4040
Main Authors: Lin, Peng, Luo, Xiaoteng, Hsing, I-Ming, Yan, Feng
Format: Article
Language:English
Subjects:
DNA - analysis
DNA Probes - chemistry
DNA sensors
Electrochemical Techniques - instrumentation
Electrochemical Techniques - methods
Electrodes
flexible electronics
Gold - chemistry
Microfluidic Analytical Techniques - instrumentation
Microfluidic Analytical Techniques - methods
microfluidic channels
Nucleic Acid Hybridization - methods
organic electrochemical transistors
organic thin-film transistors
Polystyrenes - chemistry
Thiophenes - chemistry
Transistors, Electronic
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Summary:Organic electrochemical transistors are integrated in flexible microfluidic systems. A novel label‐free DNA sensor is developed based on the devices with single‐stranded DNA probes immobilized on gate electrodes. These devices successfully detect complementary DNA targets at low concentrations using a pulse‐enhanced hybridization technique in microfluidic channels. Organic electrochemical transistors are excellent candidates for flexible, highly sensitive, and low‐cost biosensors.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201102017