A ternary tetracoordinated Pd II complex with metformin and dipicolinate: Synthesis, characterization and crystal structure

• Published in: Journal of molecular structure 2011-06, Vol.996 (1), p.38-41
• Main Authors: Moghimi, A., Khavassi, H.R., Dashtestani, F., Kordestani, D., Ekram Jafari, A., Maddah, B., Moosavi, S.M.
• Format: Article
• Language: English
• Subjects: 2,6-Pyridinedicarboxylic acid; Complex; Crystal structure; Crystals; Infrared radiation; Ligands; Metformin; NMR spectroscopy; Pd II complex; Synthesis; X-ray; X-rays
• ISSN: 0022-2860; 1872-8014
• DOI: 10.1016/j.molstruc.2011.03.061

► We present an approach to make a ternary tetracoordinated Pd II complex. ► This complex involves metformine and dipicolinic acid, the known compounds in diabets treatment researches, as ligands. ► The dipicolinic acid is coordinated to the metal in a bidentate manner. ► Dipicolinic acid in most of the corresponding metal complexes behaves as a tridentate ligand. ► Synthesis of such vanadium complexes may improve the potential and possible synergy effect for the diabets treatment. A proton transfer compound L, (MetH) 2(dipic), (dipicH 2 = 2,6-pyridinedicarboxylic acid and Met = Metformin (N,N-dimethylebiguanidine), was synthesized and characterized by IR, 1H and 13C NMR spectroscopy. The reaction of L with PdCl 2 in water results in the formation of novel tetracoordinated Pd II complex [Pd(dipic)(Met)]·2H 2O indicating the participation of both dipic 2− and Met as chelating ligands. This complex was characterized by single crystal X-ray analysis. The crystal system is monoclinic with space group P2 1/c. The unit cell dimensions for Pd II complex 1 is a = 8.8619(14) Å, b = 9.5072(9) Å, c = 19.153(3) Å.