Unmatched projector/backprojector pair for demultiplexing in multipinhole emission computed tomography

Statistically based iterative algorithms such as maximum likelihood-expectation maximization (ML-EM) are used for image reconstruction in single photon emission computed tomography (SPECT). Unmatched projector/backprojector pairs are sometimes used to accelerate the iteration process in the reconstr...

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Bibliographic Details
Published in:Optical Engineering 2010-12, Vol.49 (12), p.127004-127004
Main Authors: Min, Byung Jun, Choi, Yong, Lee, Nam-Yong, Jung, Jin Ho, Hong, Key Jo, Kang, Ji Hoon, Hu, Wei, Lee, Kisung, Ahn, Young Bok, Joung, Jinhun
Format: Article
Language:English
Subjects:
Algorithms
Demultiplexing
Mathematical models
Multiplexing
Projectors
Reconstruction
Tomography
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Summary:Statistically based iterative algorithms such as maximum likelihood-expectation maximization (ML-EM) are used for image reconstruction in single photon emission computed tomography (SPECT). Unmatched projector/backprojector pairs are sometimes used to accelerate the iteration process in the reconstruction algorithm. In this work, we propose and explore the use of an unmatched projector/backprojector pair for demultiplexing in multipinhole SPECT. Several simulations are conducted to evaluate the performance of the proposed method with uniform, hot-rod, and cold-rod phantoms. The proposed method incorporates an unmatched backprojector to utilize selective multiplexed projection data in reconstruction algorithms, while the projector is modeled as accurately as possible to represent realistic imaging geometry and the physical effects of multipinhole SPECT. The root mean square (rms) error and backprojection speed are evaluated to determine an unmatched backprojector. Our results demonstrate that the proposed method provides high-quality multipinhole SPECT images without multiplexing-related artifacts when a well-chosen unmatched backprojector is used.
ISSN:0091-3286
1560-2303
DOI:10.1117/1.3518081