Predicting left ventricular dysfunction after valve repair for mitral regurgitation due to leaflet prolapse: additive value of left ventricular end-systolic dimension to ejection fraction

• Published in: European journal of echocardiography 2011-09, Vol.12 (9), p.702-710
• Main Authors: Tribouilloy, Christophe, Rusinaru, Dan, Szymanski, Catherine, Mezghani, Sonia, Fournier, Alexandre, Lévy, Franck, Peltier, Marcel, Ben Ammar, Ammar, Carmi, Doron, Remadi, Jean-Paul, Caus, Thierry, Touati, Gilles
• Format: Article
• Language: English
• Subjects: Aged; Echocardiography, Doppler; Female; Humans; Logistic Models; Male; Mitral Valve Insufficiency - etiology; Mitral Valve Insufficiency - surgery; Mitral Valve Prolapse - complications; Postoperative Complications - diagnosis; Proportional Hazards Models; ROC Curve; Stroke Volume; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - etiology; Ventricular Dysfunction, Left - physiopathology
• ISSN: 1525-2167; 1532-2114
• DOI: 10.1093/ejechocard/jer128

Left ventricular (LV) dysfunction is the first cause of late mortality after mitral valve surgery. In this retrospective analysis, we studied the association between preoperative echocardiographic LV measures and occurrence of LV dysfunction after mitral valve repair (MVR). Between 1991 and 2009, 335 consecutive patients underwent MVR for severe mitral regurgitation due to leaflet prolapse in our institution. Echocardiography was performed preoperatively and at 10.8 (9.1-12.0) months after surgery in 303 patients who represented the study population. Cardiac events were recorded during follow-up. LV ejection fraction (EF) decreased from 68 ± 9% before surgery to 59 ± 9% post-operatively (P < 0.001). Preoperative EF