Age at menarche, menstrual cycle characteristics and risk of gestational diabetes

Abstract Aims We examined associations of age at menarche and menstrual cycle characteristics with gestational diabetes mellitus (GDM) risk. Methods Study participants ( N = 3490) recruited prior to 16 weeks of gestation were followed until delivery. Menstrual history data were collected using quest...

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Bibliographic Details
Published in:Diabetes research and clinical practice 2011-09, Vol.93 (3), p.437-442
Main Authors: Dishi, Michal, Enquobahrie, Daniel A, Abetew, Dejene F, Qiu, Chunfang, Rudra, Carole B, Williams, Michelle A
Format: Article
Language:English
Subjects:
Adult
Confidence Intervals
Diabetes, Gestational - epidemiology
Endocrinology & Metabolism
Female
Gestational diabetes
Humans
Logistic Models
Menarche
Menarche - physiology
Menstrual cycle
Menstrual Cycle - physiology
Obesity
Odds Ratio
Pregnancy
Risk Factors
Weight gain
Young Adult
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Summary:Abstract Aims We examined associations of age at menarche and menstrual cycle characteristics with gestational diabetes mellitus (GDM) risk. Methods Study participants ( N = 3490) recruited prior to 16 weeks of gestation were followed until delivery. Menstrual history data were collected using questionnaires. GDM was diagnosed using the American Diabetes Association 2003 guidelines. Logistic regression was used to estimate odds-ratios (OR) and 95% confidence intervals (CI). Results Age at menarche was not associated with GDM risk. Women who had long menstrual cycles (>36 days) had higher risk of GDM compared with women who had normal cycle length (25–30 days) (OR = 1.6; 95%CI0.98–2.67). Women who had long menstrual cycles and were either overweight or gained >5 kg in adulthood had 4–5-fold higher GDM risk compared with women who had normal cycle length and were non-obese or gained
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2011.07.001