Mass lesions in chronic pancreatitis: benign or malignant? An “evidence-based practice” approach

The diagnosis of a pancreatic mass lesion in the presence of chronic pancreatitis can be extremely challenging. At the same time, a high level of certainty about the diagnosis is necessary for appropriate management planning. The aim of this study was to establish current best evidence about which i...

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Bibliographic Details
Published in:Abdominal imaging 2011-10, Vol.36 (5), p.569-577
Main Authors: Gerstenmaier, Jan F., Malone, Dermot E.
Format: Article
Language:English
Subjects:
Algorithms
Bayes Theorem
Biological and medical sciences
Diagnosis, Differential
Diagnostic Imaging
Evidence-Based Medicine - methods
Gastroenterology
Gastroenterology. Liver. Pancreas. Abdomen
Hepatology
Humans
Imaging
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Medicine
Medicine & Public Health
Other diseases. Semiology
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - pathology
Pancreatitis - diagnosis
Pancreatitis - pathology
Radiology
Tumors
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Summary:The diagnosis of a pancreatic mass lesion in the presence of chronic pancreatitis can be extremely challenging. At the same time, a high level of certainty about the diagnosis is necessary for appropriate management planning. The aim of this study was to establish current best evidence about which imaging methods reliably differentiate a benign from a malignant lesion, and show how that evidence is best applied. A diagnostic algorithm based on Bayesian analysis is proposed.
ISSN:0942-8925
2366-004X
1432-0509
2366-0058
DOI:10.1007/s00261-010-9658-9