Lack of association of the RTN4R genetic variations with risk of schizophrenia and SPEM abnormality in a Korean population

Abstract This study examined the association of the reticulon 4 receptor ( RTN4R ) gene with schizophrenia and smooth pursuit eye movement (SPEM) abnormality in a Korean population. Although we failed to provide convincing evidence that RTN4R is associated with schizophrenia development and SPEM imp...

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Bibliographic Details
Published in:Psychiatry research 2011-09, Vol.189 (2), p.312-314
Main Authors: Pasaje, Charisse Flerida A, Bae, Joon Seol, Park, Byung-Lae, Park, Chul Soo, Kim, Bong-Jo, Lee, Cheol-Soon, Kim, Jae Won, Choi, Woo Hyuk, Shin, Tae-Min, Koh, In Song, Choi, Ihn-Geun, Woo, Sung-ll, Shin, Hyoung Doo
Format: Article
Language:English
Subjects:
Adult and adolescent clinical studies
Biological and medical sciences
Electrooculography - methods
Female
Genetic Predisposition to Disease - genetics
Genome-Wide Association Study
GPI-Linked Proteins - genetics
Humans
Male
Medical sciences
Myelin Proteins - genetics
Nogo Receptor 1
Ocular Motility Disorders - genetics
Polymorphism, Single Nucleotide - genetics
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Pursuit, Smooth - genetics
Receptors, Cell Surface - genetics
Regression Analysis
Republic of Korea
Risk Factors
RTN4R
Schizophrenia
Schizophrenia - genetics
Single nucleotide polymorphism
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Summary:Abstract This study examined the association of the reticulon 4 receptor ( RTN4R ) gene with schizophrenia and smooth pursuit eye movement (SPEM) abnormality in a Korean population. Although we failed to provide convincing evidence that RTN4R is associated with schizophrenia development and SPEM impairment, our findings may be useful for further genetic studies.
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2011.02.006