End-of-life opioid administration on neonatal and pediatric intensive care units: Nurses’ attitudes and practice

• Published in: European journal of pain 2011-10, Vol.15 (9), p.958-965
• Main Authors: Garten, Lars, Daehmlow, Steffen, Reindl, Tobias, Wendt, Anke, Münch, Annette, Bührer, Christoph
• Format: Article
• Language: English
• Subjects: Analgesia - statistics & numerical data; Analgesics, Opioid - administration & dosage; Anesthesia & Perioperative Care; Attitude of Health Personnel; Child; Children; Dying; Ethics; Health Knowledge, Attitudes, Practice; Humans; Infant; Infant, Newborn; Infants; Intensive Care Units, Neonatal - statistics & numerical data; Intensive Care Units, Pediatric - statistics & numerical data; Neonate; Pain Medicine; Pediatric Nursing - statistics & numerical data; Premature infant; Retrospective Studies; Terminal Care - statistics & numerical data; Withhold
• ISSN: 1090-3801; 1532-2149
• DOI: 10.1016/j.ejpain.2011.03.009

Abstract Objectives (1) To compare caregivers attitudes on the use of end-of-life opioid analgesia in neonatal (NICU) and pediatric (PICU) intensive care units. (2) To investigate actual opioid administration to DR (delivery room), NICU and PICU patients in various end-of-life situations. Methods (1) Administration of an anonymous self-report questionnaire survey to nurses of 2 level III NICUs and 3 PICUs, presenting 5 hypothetical NICU and PICU patients in end-of-life situations. (2) Retrospective chart review of all deaths at the above mentioned DRs (served by NICU staff), NICUs and PICUs during the years 2008–2009. Results There was no difference between NICU and PICU nurses in self-proclaimed opioid administration in dying NICU or PICU patients with signs of pain (about 80%) or distress (about 65%). 35.0% of NICU and 44.5% of PICU nurses favoured opioid administration with the implicit aim of active intentional ending of life. Shortening of life as an adverse effect of end-of-life opioid analgesia was acceptable for the majority of PICU (94.5%) and NICU (87.0%) nurses. The rate of dying infants who actually had received opioids was similar in NICUs (41/74, 55.4%) and PICUs (40/68, 58.8%). In contrast, none of the neonates ( n = 24) who died under primary comfort care in the DR received opioids. Conclusions End-of-life opioid administration to primary comfort care patients in the DR differs fundamentally from NICU or PICU handling of dying patients. Once patients are admitted to an intensive care unit, practice and attitudes towards end-of-life opioid administration are similar in NICUs and PICUs.