Enantioselective organocatalytic formal allylation of α-branched aldehydes

Heteroarylvinyl sulfone 1 has been successfully used as a new sulfonyl Michael acceptor in aminocatalytic reactions with branched aldehydes. Subsequent one-pot Julia-Kocienski olefination allows the challenging preparation of enantiomerically pure α-allylated aldehydes bearing C-α quaternary carbons...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2011-10, Vol.47 (40), p.11267-11269
Main Authors: Rodrigo, Eduardo, Morales, Sara, Duce, Sara, Ruano, José Luis García, Cid, M Belén
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Heteroarylvinyl sulfone 1 has been successfully used as a new sulfonyl Michael acceptor in aminocatalytic reactions with branched aldehydes. Subsequent one-pot Julia-Kocienski olefination allows the challenging preparation of enantiomerically pure α-allylated aldehydes bearing C-α quaternary carbons.
ISSN:1359-7345
1364-548X
DOI:10.1039/c1cc14909a