Rubella Vaccination of Unknowingly Pregnant Women During 2006 Mass Campaign in Argentina

We report a prospective study of 56 pregnant women inadvertently vaccinated with rubella vaccine during the 2006 campaign performed in Argentina. Of these patients, 48 (87%) were immune, whereas the remaining 9 (16%) were susceptible. In the latter group, 7 presented with a primary reaction to the v...

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Bibliographic Details
Published in:The Journal of infectious diseases 2011-09, Vol.204 (suppl_2), p.S745-S747
Main Authors: Pardon, Fabian, Vilariño, Mariana, Barbero, Pablo, Garcia, Gabriela, Outon, Estela, Gil, Cecilia, Vera, Alejandra, Rossi, Silvana, Distefano, Angelica
Format: Article
Language:English
Subjects:
Antibodies, Viral - blood
Argentina - epidemiology
Communicable Disease Control
Congenital rubella syndrome
Female
Humans
Immunoglobulin G - blood
Immunoglobulin M - blood
Infant, Newborn
Mass Vaccination - adverse effects
Newborns
Obstetric labor complications
Pregnancy
Pregnancy Complications, Infectious
Rubella
Rubella - congenital
Rubella - prevention & control
Rubella Vaccine - administration & dosage
Rubella Vaccine - adverse effects
Rubella Vaccine - immunology
Rubella vaccines
SAFETY ISSUES
Symptoms
Vaccination
Viruses
Women
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Summary:We report a prospective study of 56 pregnant women inadvertently vaccinated with rubella vaccine during the 2006 campaign performed in Argentina. Of these patients, 48 (87%) were immune, whereas the remaining 9 (16%) were susceptible. In the latter group, 7 presented with a primary reaction to the vaccine confirmed through immunoglobulin (Ig) G antibody avidity testing or seroconversion of IgG titers. During the clinical and laboratory follow-up, newborns did not present evidence of infection or malformations compatible with congenital rubella syndrome.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/jir442