Secondary prevention of fractures and compliance to treatment in osteoporosis

Osteoporosis is a mechanical incompetence of bone which finally leads to fracture. The occurrence of a fracture for a minor trauma is the definitive evidence of bone fragility and an indication of an higher probability for other fractures. Fracture at any site is a strong risk factor for a subsequen...

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Bibliographic Details
Published in:Aging clinical and experimental research 2011-04, Vol.23 (2 Suppl), p.22-24
Main Author: Trevisan, Carlo
Format: Article
Language:English
Subjects:
Aged
Bone Density Conservation Agents - therapeutic use
Clinical Trials as Topic
Cost-Benefit Analysis
Female
Humans
Medication Adherence
Middle Aged
Osteoporosis - complications
Osteoporosis - therapy
Osteoporotic Fractures - prevention & control
Physician-Patient Relations
Recurrence
Risk
Secondary Prevention
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Summary:Osteoporosis is a mechanical incompetence of bone which finally leads to fracture. The occurrence of a fracture for a minor trauma is the definitive evidence of bone fragility and an indication of an higher probability for other fractures. Fracture at any site is a strong risk factor for a subsequent fracture, therefore any patient with a prevalent fracture is an ideal candidate for treatment due to the high risk for recurrence and to a favourable cost-benefit ratio. Most of the available pharmacological agents approved for osteoporosis treatment are effective in reducing fracture risk in this class of patients. Unfortunately, poor compliance is very common in patients treated for osteoporosis and this leads to reduced benefits and ineffectual costs. Dose regimen simplification is neither the only nor the most important solution to improve compliance, and a multifaceted strategy targeting cognitive, behavioural and emotional factors should be employed.
ISSN:1594-0667