An Automated Fluid-transport Device for a Microfluidic System

An automated fluid-transport device for a chip-based capillary electrophoresis system has been developed. The device mainly consists of six peristaltic micropumps, two vacuum micropumps, microvalves, multi-way joints, titanium tubes, and a macro-to-micro connector. Various solutions used for the cle...

Full description

Saved in:
Bibliographic Details
Published in:Analytical Sciences 2011/10/10, Vol.27(10), pp.1057-1057
Main Authors: FENG, Jun, YANG, Xiu-Juan, LI, Xin-Chun, YANG, Hui, CHEN, Zuan-Guang
Format: Article
Language:English
Subjects:
Advancements in Instrumentation
Analytical Chemistry
Automation
Chemistry
Electrophoresis, Capillary
Fluorescein - analysis
Fluorescence
Microfluidic Analytical Techniques - instrumentation
Microfluidic Analytical Techniques - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An automated fluid-transport device for a chip-based capillary electrophoresis system has been developed. The device mainly consists of six peristaltic micropumps, two vacuum micropumps, microvalves, multi-way joints, titanium tubes, and a macro-to-micro connector. Various solutions used for the cleaning and activation of chip channels, and electrophoresis separation, are allowed to automatically transport to chip reservoirs by the electric control module. The performance of the whole system was characterized by the analysis of fluorescein sodium using chip electrophoresis with LED-induced fluorescence detection. The peak-height variation (RSD) was 3.8% in six cycles of analyses. Additionally, compared with conventional manual operation, the developed device can spare 60% time for chip pretreatment. This microdevice offers high-efficiency pretreatment for microchips, thereby resulting in a remarkable improvement of analytical capacity for batch samples.
ISSN:0910-6340
1348-2246
DOI:10.2116/analsci.27.1057