Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy

Introduction In the western world, cannabis is the most widely used drug of abuse. Cannabinoid hyperemesis syndrome, which seems to be a rare paradoxical reaction in individuals with a particular predisposition, is characterized by cyclic severe nausea and vomiting in long-term cannabis users. While...

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Bibliographic Details
Published in:Archives of gynecology and obstetrics 2011-11, Vol.284 (5), p.1095-1097
Main Authors: Schmid, Seraina M., Lapaire, Olav, Huang, Dorothy J., Jürgens, Frank Edwin, Güth, Uwe
Format: Article
Language:English
Subjects:
Adult
Antiemetics - therapeutic use
Baths
Cannabinoids - adverse effects
Cannabinoids - urine
Endocrinology
Female
Gynecology
Human Genetics
Humans
Hydrotherapy - methods
Hyperemesis Gravidarum - chemically induced
Hyperemesis Gravidarum - drug therapy
Hyperemesis Gravidarum - urine
Marijuana
Materno-Fetal Medicine
Medicine
Medicine & Public Health
Nausea
Nausea - chemically induced
Nausea - therapy
Obstetrics/Perinatology/Midwifery
Pregnancy
Pregnancy Trimester, First
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Summary:Introduction In the western world, cannabis is the most widely used drug of abuse. Cannabinoid hyperemesis syndrome, which seems to be a rare paradoxical reaction in individuals with a particular predisposition, is characterized by cyclic severe nausea and vomiting in long-term cannabis users. While the symptoms are unresponsive to antiemetic drugs, compulsive hot baths result in a considerable symptom relief. Methods We report the first case of cannabinoid hyperemesis syndrome in pregnancy. A 26-year-old patient was admitted to our clinic in the 10th week of gestation. Conclusion Before undertaking time-consuming and expensive medical examinations to rule out other medical reasons for therapy-resistant hyperemesis in pregnancy, obstetricians should determine whether compulsive bathing or showering provides symptomatic relief and ask specific questions regarding possible/suspected cannabis consumption.
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-010-1811-8