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Clinical comparison between a continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane with an interrupted Lembert pattern for one-layer jejunojejunostomy in horses

Reasons for performing study: Although experimental studies have demonstrated differences in performance between methods for handsewn jejunojejunostomy in horses, information on clinical results after different methods of anastomosis are rare. Hypothesis: A continuous Lembert pattern wrapped in a ca...

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Published in:Equine veterinary journal 2011-11, Vol.43 (6), p.708-713
Main Authors: Freeman, D.E, Schaeffer, D.J
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Language:English
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Schaeffer, D.J
description Reasons for performing study: Although experimental studies have demonstrated differences in performance between methods for handsewn jejunojejunostomy in horses, information on clinical results after different methods of anastomosis are rare. Hypothesis: A continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane would perform better than an interrupted Lembert pattern for jejunojejunostomy in horses. Methods: Data was reviewed on 32 horses that underwent jejunojejunostomy from 1993–2002. Kaplan-Meier analyses and rates for post operative colic and death were used to compare outcomes after an interrupted Lembert pattern (15 horses with strangulating lesions and 5 horses with nonstrangulating lesions) and a continuous Lembert pattern with membrane (12 horses with strangulating diseases). Results: None of the 32 horses had post operative ileus or post operative endotoxaemia. One horse with a continuous pattern required a repeat celiotomy for anastomotic impaction. Short-term survivals for the interrupted Lembert were 100% (nonstrangulating lesions) and 93% (strangulating lesions) and for the continuous pattern 92% (all strangulating). Long-term rates for mortality and colic episodes were less for the continuous Lembert pattern with membrane compared with the interrupted Lembert for strangulating lesions (P
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Hypothesis: A continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane would perform better than an interrupted Lembert pattern for jejunojejunostomy in horses. Methods: Data was reviewed on 32 horses that underwent jejunojejunostomy from 1993–2002. Kaplan-Meier analyses and rates for post operative colic and death were used to compare outcomes after an interrupted Lembert pattern (15 horses with strangulating lesions and 5 horses with nonstrangulating lesions) and a continuous Lembert pattern with membrane (12 horses with strangulating diseases). Results: None of the 32 horses had post operative ileus or post operative endotoxaemia. One horse with a continuous pattern required a repeat celiotomy for anastomotic impaction. Short-term survivals for the interrupted Lembert were 100% (nonstrangulating lesions) and 93% (strangulating lesions) and for the continuous pattern 92% (all strangulating). Long-term rates for mortality and colic episodes were less for the continuous Lembert pattern with membrane compared with the interrupted Lembert for strangulating lesions (P&lt;0.05) and were less for strangulating lesions than for nonstrangulating lesions (P&lt;0.05). For strangulating lesions, Kaplan-Meier analyses yielded a survival probability of 70% for up to 9 years after the interrupted Lembert pattern and 80% for up to 5 years for the continuous Lembert pattern. Conclusions and relevance: Both Lembert patterns performed well in clinical use, although the continuous pattern with the carboxymethylcellulose and hyaluronate membrane had superior long-term outcomes with less colic and mortality from colic.</description><identifier>ISSN: 0425-1644</identifier><identifier>EISSN: 2042-3306</identifier><identifier>DOI: 10.1111/j.2042-3306.2010.00340.x</identifier><identifier>PMID: 21815916</identifier><identifier>CODEN: EQVJAI</identifier><language>eng</language><publisher>Oxford, UK: British Equine Veterinary Association</publisher><subject>Aging ; Animals ; carboxymethylcellulose ; Carboxymethylcellulose Sodium ; colic ; death ; endotoxemia ; Gastrointestinal Diseases - surgery ; Gastrointestinal Diseases - veterinary ; horse ; Horse Diseases - surgery ; Horses ; Hyaluronic Acid ; intestinal obstruction ; jejunojejunostomy ; Jejunostomy - methods ; Jejunostomy - veterinary ; mortality ; post operative ileus ; probability ; Retrospective Studies ; survival ; Suture Techniques - veterinary</subject><ispartof>Equine veterinary journal, 2011-11, Vol.43 (6), p.708-713</ispartof><rights>2011 EVJ Ltd</rights><rights>2011 EVJ Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4570-a1849ed0618ea72df2396b693c032ed7a4a4e88be2f758bb2ac106d41a570c173</citedby><cites>FETCH-LOGICAL-c4570-a1849ed0618ea72df2396b693c032ed7a4a4e88be2f758bb2ac106d41a570c173</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21815916$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Freeman, D.E</creatorcontrib><creatorcontrib>Schaeffer, D.J</creatorcontrib><title>Clinical comparison between a continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane with an interrupted Lembert pattern for one-layer jejunojejunostomy in horses</title><title>Equine veterinary journal</title><addtitle>Equine Vet J</addtitle><description>Reasons for performing study: Although experimental studies have demonstrated differences in performance between methods for handsewn jejunojejunostomy in horses, information on clinical results after different methods of anastomosis are rare. Hypothesis: A continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane would perform better than an interrupted Lembert pattern for jejunojejunostomy in horses. Methods: Data was reviewed on 32 horses that underwent jejunojejunostomy from 1993–2002. Kaplan-Meier analyses and rates for post operative colic and death were used to compare outcomes after an interrupted Lembert pattern (15 horses with strangulating lesions and 5 horses with nonstrangulating lesions) and a continuous Lembert pattern with membrane (12 horses with strangulating diseases). Results: None of the 32 horses had post operative ileus or post operative endotoxaemia. One horse with a continuous pattern required a repeat celiotomy for anastomotic impaction. Short-term survivals for the interrupted Lembert were 100% (nonstrangulating lesions) and 93% (strangulating lesions) and for the continuous pattern 92% (all strangulating). Long-term rates for mortality and colic episodes were less for the continuous Lembert pattern with membrane compared with the interrupted Lembert for strangulating lesions (P&lt;0.05) and were less for strangulating lesions than for nonstrangulating lesions (P&lt;0.05). For strangulating lesions, Kaplan-Meier analyses yielded a survival probability of 70% for up to 9 years after the interrupted Lembert pattern and 80% for up to 5 years for the continuous Lembert pattern. Conclusions and relevance: Both Lembert patterns performed well in clinical use, although the continuous pattern with the carboxymethylcellulose and hyaluronate membrane had superior long-term outcomes with less colic and mortality from colic.</description><subject>Aging</subject><subject>Animals</subject><subject>carboxymethylcellulose</subject><subject>Carboxymethylcellulose Sodium</subject><subject>colic</subject><subject>death</subject><subject>endotoxemia</subject><subject>Gastrointestinal Diseases - surgery</subject><subject>Gastrointestinal Diseases - veterinary</subject><subject>horse</subject><subject>Horse Diseases - surgery</subject><subject>Horses</subject><subject>Hyaluronic Acid</subject><subject>intestinal obstruction</subject><subject>jejunojejunostomy</subject><subject>Jejunostomy - methods</subject><subject>Jejunostomy - veterinary</subject><subject>mortality</subject><subject>post operative ileus</subject><subject>probability</subject><subject>Retrospective Studies</subject><subject>survival</subject><subject>Suture Techniques - veterinary</subject><issn>0425-1644</issn><issn>2042-3306</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqNks1u1DAUhSMEokPhFcASC1YZbMf5k9igaWmLhiKghaXlJDdMQmIH29FMno8X46Yps-iKSE6u7O-ca_skCAija4bP23bNqeBhFNEEK5ylNBJ0fXgUrI4Lj4MVlnHIEiFOgmfOtQhFXPCnwQlnGYtzlqyCP5uu0U2pOlKaflC2cUaTAvweQBOFk9o3ejSjI1voC7CeDMp7sJrsrRoGqEhzxylbmMPUg99NXQldN3bGAVG6IrtJdaM1WnkgPXpYpYHsG7_DVRSjlx0Hj0YPG9TGEqMh7NQElrTQjtosb-dNP82Nd8Y6cM-DJ7XqHLy4_54Gtx_ObzaX4fbzxdXm_TYsRZzSULFM5FDRhGWgUl7VPMqTIsmjkkYcqlQJJSDLCuB1GmdFwVXJaFIJplBdsjQ6Dd4svoM1v0dwXvaNmw-LJ8IbklmesZQlnCH5-gHZmtFq3JxkMUt5lookQipbqNIa5yzUcrBNr-wkGZVzzrKVc5xyjlPOOcu7nOUBpS_vG4xFD9VR-C9YBN4twL7pYPpvY3n-_SMWKA8XeeM8HI5yZX_JJI3SWP64vpBfoq83Z5_4tcyRf7XwtTJS_cTfSN5-Q-OY4hAcN_QXA23T8g</recordid><startdate>201111</startdate><enddate>201111</enddate><creator>Freeman, D.E</creator><creator>Schaeffer, D.J</creator><general>British Equine Veterinary Association</general><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201111</creationdate><title>Clinical comparison between a continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane with an interrupted Lembert pattern for one-layer jejunojejunostomy in horses</title><author>Freeman, D.E ; Schaeffer, D.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4570-a1849ed0618ea72df2396b693c032ed7a4a4e88be2f758bb2ac106d41a570c173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aging</topic><topic>Animals</topic><topic>carboxymethylcellulose</topic><topic>Carboxymethylcellulose Sodium</topic><topic>colic</topic><topic>death</topic><topic>endotoxemia</topic><topic>Gastrointestinal Diseases - surgery</topic><topic>Gastrointestinal Diseases - veterinary</topic><topic>horse</topic><topic>Horse Diseases - surgery</topic><topic>Horses</topic><topic>Hyaluronic Acid</topic><topic>intestinal obstruction</topic><topic>jejunojejunostomy</topic><topic>Jejunostomy - methods</topic><topic>Jejunostomy - veterinary</topic><topic>mortality</topic><topic>post operative ileus</topic><topic>probability</topic><topic>Retrospective Studies</topic><topic>survival</topic><topic>Suture Techniques - veterinary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Freeman, D.E</creatorcontrib><creatorcontrib>Schaeffer, D.J</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Equine veterinary journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Freeman, D.E</au><au>Schaeffer, D.J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical comparison between a continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane with an interrupted Lembert pattern for one-layer jejunojejunostomy in horses</atitle><jtitle>Equine veterinary journal</jtitle><addtitle>Equine Vet J</addtitle><date>2011-11</date><risdate>2011</risdate><volume>43</volume><issue>6</issue><spage>708</spage><epage>713</epage><pages>708-713</pages><issn>0425-1644</issn><eissn>2042-3306</eissn><coden>EQVJAI</coden><abstract>Reasons for performing study: Although experimental studies have demonstrated differences in performance between methods for handsewn jejunojejunostomy in horses, information on clinical results after different methods of anastomosis are rare. Hypothesis: A continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane would perform better than an interrupted Lembert pattern for jejunojejunostomy in horses. Methods: Data was reviewed on 32 horses that underwent jejunojejunostomy from 1993–2002. Kaplan-Meier analyses and rates for post operative colic and death were used to compare outcomes after an interrupted Lembert pattern (15 horses with strangulating lesions and 5 horses with nonstrangulating lesions) and a continuous Lembert pattern with membrane (12 horses with strangulating diseases). Results: None of the 32 horses had post operative ileus or post operative endotoxaemia. One horse with a continuous pattern required a repeat celiotomy for anastomotic impaction. Short-term survivals for the interrupted Lembert were 100% (nonstrangulating lesions) and 93% (strangulating lesions) and for the continuous pattern 92% (all strangulating). Long-term rates for mortality and colic episodes were less for the continuous Lembert pattern with membrane compared with the interrupted Lembert for strangulating lesions (P&lt;0.05) and were less for strangulating lesions than for nonstrangulating lesions (P&lt;0.05). For strangulating lesions, Kaplan-Meier analyses yielded a survival probability of 70% for up to 9 years after the interrupted Lembert pattern and 80% for up to 5 years for the continuous Lembert pattern. Conclusions and relevance: Both Lembert patterns performed well in clinical use, although the continuous pattern with the carboxymethylcellulose and hyaluronate membrane had superior long-term outcomes with less colic and mortality from colic.</abstract><cop>Oxford, UK</cop><pub>British Equine Veterinary Association</pub><pmid>21815916</pmid><doi>10.1111/j.2042-3306.2010.00340.x</doi><tpages>6</tpages></addata></record>
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language eng
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subjects Aging
Animals
carboxymethylcellulose
Carboxymethylcellulose Sodium
colic
death
endotoxemia
Gastrointestinal Diseases - surgery
Gastrointestinal Diseases - veterinary
horse
Horse Diseases - surgery
Horses
Hyaluronic Acid
intestinal obstruction
jejunojejunostomy
Jejunostomy - methods
Jejunostomy - veterinary
mortality
post operative ileus
probability
Retrospective Studies
survival
Suture Techniques - veterinary
title Clinical comparison between a continuous Lembert pattern wrapped in a carboxymethylcellulose and hyaluronate membrane with an interrupted Lembert pattern for one-layer jejunojejunostomy in horses
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