The antibiotic R&D pipeline: an update

Highlights ► The commercial and social environments that led to the ‘antibiotic crisis’ are reviewed. ► Most recent data on antibiotics in discovery and development are reported. ► All main scaffolds, from synthetic or natural source and related compounds, are described.

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Bibliographic Details
Published in:Current opinion in microbiology 2011-10, Vol.14 (5), p.564-569
Main Author: Jabes, Daniela
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - pharmacology
antibiotics
bacteria
Bacteria - drug effects
Biological and medical sciences
Drug Discovery - trends
drugs
Fundamental and applied biological sciences. Psychology
Humans
Microbiology
multiple drug resistance
Pathology
Research - trends
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Description
Summary:Highlights ► The commercial and social environments that led to the ‘antibiotic crisis’ are reviewed. ► Most recent data on antibiotics in discovery and development are reported. ► All main scaffolds, from synthetic or natural source and related compounds, are described.
ISSN:1369-5274
1879-0364
DOI:10.1016/j.mib.2011.08.002