Infant Delirium in Pediatric Critical Care Settings

From research in traumatic brain injury, epilepsy, and meningitis, it is clear that the immature brain has different responses to oxygen deprivation and cytokine release compared to the adult brain (9). Because delirium may represent "end organ damage" of the brain in critical illness, lon...

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Bibliographic Details
Published in:The American journal of psychiatry 2010-10, Vol.167 (10), p.1172-1177
Main Authors: Silver, Gabrielle H., Kearney, Julia A., Kutko, Martha C., Bartell, Abraham S.
Format: Article
Language:English
Subjects:
Adolescent
Adult and adolescent clinical studies
Antipsychotic Agents - administration & dosage
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
Biological and medical sciences
Brain
Child
Child, Preschool
Children & youth
Cognition & reasoning
Critical Illness - therapy
Delirium - drug therapy
Dopamine
Female
Hospitals
Humans
Illnesses
Infant
Intensive Care Units, Pediatric - organization & administration
Medical sciences
Medical treatment
Mortality
Neuroprotective Agents - administration & dosage
Neuroprotective Agents - therapeutic use
Organic mental disorders. Neuropsychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychotropic drugs
Treatment Outcome
Validation studies
Ventilation
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Description
Summary:From research in traumatic brain injury, epilepsy, and meningitis, it is clear that the immature brain has different responses to oxygen deprivation and cytokine release compared to the adult brain (9). Because delirium may represent "end organ damage" of the brain in critical illness, long-term neurocognitive outcome studies in child survivors of untreated delirium are needed.
ISSN:0002-953X
1535-7228
DOI:10.1176/appi.ajp.2010.09111606