P1-476 An assessment of the concentration-related prognostic value of cardiac troponin I in 1285 patients following acute coronary syndrome

IntroductionThe British Cardiac Society, in 2004, redefined myocardial infarction by troponin concentration: cTnI ≤0.06 μg/l (unstable angina), cTnI >0.06 μg/l to 0.06 and 80 years (3.30, 3.50 to 5.06), peripheral vascular disease (1.50, 1.16 to 1.94), heart failure (1.36, 1.05 to 1.83), diabetes...

Full description

Saved in:
Bibliographic Details
Published in:Journal of epidemiology and community health (1979) 2011-08, Vol.65 (Suppl 1), p.A198-A199
Main Authors: Gale, C P, Metcalfe, E, Simms, A D, West, R, Morrell, C, Munyombwe, T, Harrison, W, Batin, P D, Hall, A S, Barth, J H
Format: Article
Language:English
Subjects:
Age
aspirin
classification
diabetes mellitus
Mortality
Myocardial infarction
Statins
Stratification
survival
Vascular diseases
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:IntroductionThe British Cardiac Society, in 2004, redefined myocardial infarction by troponin concentration: cTnI ≤0.06 μg/l (unstable angina), cTnI >0.06 μg/l to 0.06 and 80 years (3.30, 3.50 to 5.06), peripheral vascular disease (1.50, 1.16 to 1.94), heart failure (1.36, 1.05 to 1.83), diabetes (1.68, 1.36 to 2.07), severe LV dysfunction (1.50, 1.00 to 2.21) and creatinine per 10 μmol/l (1.65, 1.02 to 1.08), whereas ages 50 to 60 years (0.55, 0.32 to 0.96), β blockers (0.53, 0.44 to 0.64), aspirin (0.80 0.65 to 0.99), ACE inhibitors (0.67, 0.56 to 0.80), statins (0.73, 0.59 to 0.90) and revascularisation (0.33, 0.12 to 0.92) lowered the risk of death.ConclusionQuantitative evaluation of cTnI concentration in ACS patients with a cTnI>0.06 μg/l is associated with no added prognostic information. However, the dichotomisation of patients by cTnI status (“positive” and “negative”) continues to facilitate ACS risk stratification.
ISSN:0143-005X
1470-2738
DOI:10.1136/jech.2011.142976g.65