Particulate matter–induced hypersusceptibility to infection

[...]we have recently shown that nanosize particle (average size, 20 nm)-rich diesel exhaust particles can activate both hematopoietic and nonhematopoietic cells in vitro,7 implicating eradicating potential against xenobiotics. [...]insight into PM toxicology is required to clarify the size-dependen...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2011-10, Vol.128 (4), p.906-906
Main Authors: Inoue, Ken-ichiro, MD, PhD, Takano, Hirohisa, MD, PhD
Format: Article
Language:English
Subjects:
Allergy and Immunology
Bacterial Adhesion - drug effects
Bacterial Adhesion - physiology
Bacterial infections
Epithelial Cells - microbiology
Humans
Particulate Matter - pharmacology
Platelet Membrane Glycoproteins - metabolism
Receptors, G-Protein-Coupled - metabolism
Respiratory System - cytology
Rodents
Streptococcus infections
Streptococcus pneumoniae - physiology
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Summary:[...]we have recently shown that nanosize particle (average size, 20 nm)-rich diesel exhaust particles can activate both hematopoietic and nonhematopoietic cells in vitro,7 implicating eradicating potential against xenobiotics. [...]insight into PM toxicology is required to clarify the size-dependent effects of PM, including nano-level particles, on respiratory immune system responses.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2011.05.040