Seasonal influenza: The burden of disease in children

During the past decade, accumulating data on the impact of influenza virus-related disease in children have become available. In this review, we summarize and discuss these data. We conclude that mortality due to influenza in children is relatively limited. But, in contrast, influenza-related hospit...

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Bibliographic Details
Published in:Vaccine 2011-10, Vol.29 (43), p.7524-7528
Main Authors: Fraaij, Pieter L.A, Heikkinen, Terho
Format: Article
Language:English
Subjects:
Age
Allergy and Immunology
burden of disease
Child
Child, Preschool
Children
Cost of Illness
Cytokines
Disease
Epidemiology
Hospitalization
Humans
Infections
Influenza
Influenza Vaccines
Influenza, Human - complications
Influenza, Human - epidemiology
Influenza, Human - immunology
Influenza, Human - mortality
Intensive care
Mortality
Pandemics
Pathogenesis
Population
Respiratory tract
vaccines
Virus
Viruses
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Description
Summary:During the past decade, accumulating data on the impact of influenza virus-related disease in children have become available. In this review, we summarize and discuss these data. We conclude that mortality due to influenza in children is relatively limited. But, in contrast, influenza-related hospitalizations occur frequently. The bulk of the influenza-related disease burden is experienced in the outpatient setting. This results in sometimes very high consultation rates, frequent complications, and substantial parental work absenteeism.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.08.010