Magnetic mesoporous carbonated hydroxyapatite microspheres with hierarchical nanostructure for drug delivery systems

Magnetic mesoporous carbonated hydroxyapatite microspheres have been fabricated hydrothermally by using CaCO(3)/Fe(3)O(4) microspheres as sacrificial templates. The high drug-loading capacity and sustained drug release property suggest that the multifunctional microspheres have great potentials for...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2011-11, Vol.47 (44), p.12215-12217
Main Authors: Guo, Ya-Ping, Guo, Li-Hua, Yao, Yong-bo, Ning, Cong-Qin, Guo, Ya-Jun
Format: Article
Language:English
Subjects:
Biocompatible Materials - chemistry
Calcium Carbonate - chemistry
Drug Carriers
Durapatite - chemistry
Ferrosoferric Oxide - chemistry
Magnets
Microscopy, Electron, Scanning
Microspheres
Nanostructures - chemistry
Nanostructures - ultrastructure
Porosity
Vancomycin - chemistry
X-Ray Diffraction
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Summary:Magnetic mesoporous carbonated hydroxyapatite microspheres have been fabricated hydrothermally by using CaCO(3)/Fe(3)O(4) microspheres as sacrificial templates. The high drug-loading capacity and sustained drug release property suggest that the multifunctional microspheres have great potentials for bone-implantable drug-delivery applications.
ISSN:1359-7345
1364-548X
DOI:10.1039/c1cc15190h