Food-derived oligosaccharides exhibit pharmaceutical properties

Breast feeding is considered as the best nutrition for growth and development of an infant. Human milk consists of a unique combination of nutritional components each with different characteristics. Oligosaccharides or non-digestible carbohydrates as one of these components, are generally accepted t...

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Bibliographic Details
Published in:European journal of pharmacology 2011-09, Vol.668, p.S117-S123
Main Authors: Rijnierse, Anneke, Jeurink, Prescilla V., van Esch, Betty C.A.M., Garssen, Johan, Knippels, Léon M.J.
Format: Article
Language:English
Subjects:
Allergy
Animals
Biological and medical sciences
Breast Feeding
breast milk
Dietary Carbohydrates - pharmacology
dietary supplements
growth and development
Human milk
Humans
Immune system
Immune System Diseases - diet therapy
Immune System Diseases - drug therapy
Immune System Diseases - prevention & control
infant development
Medical sciences
Milk, Human - chemistry
nutrient content
Oligosaccharide
oligosaccharides
Oligosaccharides - pharmacology
pharmacology
Pharmacology. Drug treatments
Synbiotics
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Summary:Breast feeding is considered as the best nutrition for growth and development of an infant. Human milk consists of a unique combination of nutritional components each with different characteristics. Oligosaccharides or non-digestible carbohydrates as one of these components, are generally accepted to have a beneficial effect by selectively stimulating the growth and/or activity of one or a limited number of bacterial species. Recently more evidence is rising for direct effects of oligosaccharides on the immune system. Oligosaccharides often used as dietary supplements for their beneficial effects on the host and its immune system, are derived from nutritional sources. In this review we aim to summarize the pharmaceutical properties of these food-borne oligosaccharides early in life.
ISSN:0014-2999
1879-0712
DOI:10.1016/j.ejphar.2011.07.009