Canine Idiopathic Thrombocytopenic Purpura

Canine idiopathic thrombocytopenic purpura (ITP) is a disease in which antibodies bound to the surface of platelets mediate premature platelet destruction by macrophages. ITP in dogs and chronic ITP in humans are analogous diseases. This article draws on information from the literature on ITP in dog...

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Bibliographic Details
Published in:Journal of veterinary internal medicine 1996-07, Vol.10 (4), p.207-218
Main Authors: Lewis, David C., Meyers, Kenneth M.
Format: Article
Language:English
Subjects:
Animals
Blood Platelets - physiology
Dog Diseases
Dogs
Female
Glucocorticoids - therapeutic use
Humans
Immunoglobulins, Intravenous - therapeutic use
Immunosuppressive Agents - therapeutic use
Male
Platelet Transfusion
Purpura, Thrombocytopenic, Idiopathic - diagnosis
Purpura, Thrombocytopenic, Idiopathic - physiopathology
Purpura, Thrombocytopenic, Idiopathic - therapy
Purpura, Thrombocytopenic, Idiopathic - veterinary
Sex Characteristics
Splenectomy
Vincristine - therapeutic use
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Summary:Canine idiopathic thrombocytopenic purpura (ITP) is a disease in which antibodies bound to the surface of platelets mediate premature platelet destruction by macrophages. ITP in dogs and chronic ITP in humans are analogous diseases. This article draws on information from the literature on ITP in dogs and in humans, and reviews the pathogenesis, diagnosis, and treatment of ITP in dogs. J Vet Intern Med 1996;207–218. Copyright © 1996 by the American College of Veterinary Internal Medicine.
ISSN:0891-6640
1939-1676
DOI:10.1111/j.1939-1676.1996.tb02052.x