Penicillium aurantiogriseum Dierckx 1901: Producer of Diketopiperazine Alkaloids (Roquefortine and 3,12-Dihydroroquefortine), Isolated from Permafrost

Secondary metabolites of three strains of Penicillium aurantiogriseumisolated from permafrost sediments were identified. It was found that these fungi synthesized the diketopiperazine alkaloids roquefortine and 3,12-dihydroroquefortine. The strain VKM FW-766 synthesized alkaloids in the course of ce...

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Published in:Applied biochemistry and microbiology 2003-07, Vol.39 (4), p.393-397
Main Authors: Kozlovsky, A G, Zhelifonova, V P, Adanin, V M, Antipova, T V, Ozerskaya, S M, Ivanushkina, N E, Grafe, U
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Language:English
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Bacteria
Metabolites
Microbiology
Penicillium
Permafrost
Secondary metabolites
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container_issue 4
container_start_page 393
container_title Applied biochemistry and microbiology
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creator Kozlovsky, A G
Zhelifonova, V P
Adanin, V M
Antipova, T V
Ozerskaya, S M
Ivanushkina, N E
Grafe, U
description Secondary metabolites of three strains of Penicillium aurantiogriseumisolated from permafrost sediments were identified. It was found that these fungi synthesized the diketopiperazine alkaloids roquefortine and 3,12-dihydroroquefortine. The strain VKM FW-766 synthesized alkaloids in the course of certain growth-related processes. When the strain was grown on a mineral medium, the time courses of the roquefortine and 3,12-dihydroroquefortine concentrations were characterized by biphasic curves.[PUBLICATION ABSTRACT]
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subjects Bacteria
Metabolites
Microbiology
Penicillium
Permafrost
Secondary metabolites
title Penicillium aurantiogriseum Dierckx 1901: Producer of Diketopiperazine Alkaloids (Roquefortine and 3,12-Dihydroroquefortine), Isolated from Permafrost
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